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216100 Carboplatin - CAS 41575-94-4 - Calbiochem

Overview

Key Specifications Table

CAS #Empirical Formula
41575-94-4C₆H₁₂N₂O₄Pt

Products

Catalog NumberPackaging Qty/Pack
216100-25MG Plastic ampoule 25 mg
Description
OverviewAn analog of Cisplatin (Cat. No. 232120) with reduced nephrotoxicity. Displays potent antitumor activity.

Note: Athough soluble in DMSO, Carboplatin is reported to be rendered inactive due to ligand displacement by the nucleophilic sulfur of DMSO. Water with or without 5% glucose is recommended for solubilization prior to culture treatment.
Catalogue Number216100
Brand Family Calbiochem®
Synonymscis-Diamine[1,1-cyclobutanedicarboxylato]platinum(II), JM-8, Paraplatin
References
ReferencesHall, M.D., et al. 2014. Cancer Res. In press.
Smith, I.E., et al. 1985. Cancer Treat. Rep. 69, 43.
Harland, S.J., et al. 1984. Cancer Res. 44, 1693.
Product Information
CAS number41575-94-4
ATP CompetitiveN
FormWhite solid
Hill FormulaC₆H₁₂N₂O₄Pt
Chemical formulaC₆H₁₂N₂O₄Pt
ReversibleN
Structure formula ImageStructure formula Image
Quality LevelMQ100
Biological Information
Primary TargetPotent antitumor activity
Purity≥98% by HPLC
Physicochemical Information
Cell permeableN
Safety Information according to GHS
RTECSTP2300000
Safety Information
R PhraseR: 20/21/22-42/43-46-61

Harmful by inhalation, in contact with skin and if swallowed.
May cause sensitization by inhalation and skin contact.
May cause heritable genetic damage.
May cause harm to the unborn child.
S PhraseS: 22-26-36/37/39-45-53

Do not breathe dust.
In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
Wear suitable protective clothing, gloves and eye/face protection.
In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).
Avoid exposure - obtain special instructions before use.
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Harmful & Carcinogenic / Teratogenic
Storage +15°C to +30°C
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Global Trade Item Number
Catalog Number GTIN
216100-25MG 04055977219265