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23-055M Cardiac Troponin I, 250 µg

Full length, recombinant human Cardiac Troponin I. N-terminal c-Myc, GST-tagged. For use in Enzyme Assays. Functions as a substrate in ubiquitination assays.

Cardiac Troponin I, 250 µg MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Key Applications: Enzyme Assays
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23-055M
250 µg  
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Overview

Replacement Information

Key Specifications Table

Key ApplicationsSpeciesCascade Component
Enzyme AssaysHuman Substrate
Description
Catalogue Number23-055M
Brand Family Upstate
Trade Name
  • Upstate
DescriptionCardiac Troponin I, 250 µg
Alternate Names
  • Troponin I
  • cardiac muscle
  • TNNI3
  • TNNC1
Background InformationTroponin is a complex of three regulatory proteins (Troponin I, Troponin T and Troponin C). It is located on the actin filament and is essential for the calcium-mediated regulation of skeletal and cardiac muscle contraction. There are tissue-specific isoforms of Troponin I, T and C and two subtypes (Cardiac Troponin I and T) are released when the heart muscle has been damaged, such as during a heart attack. The more damage there is to the heart, the greater the amount of Troponin I and T there will be in the blood and currently, Cardiac Troponin I and T are used as the preferred biochemical markers for the diagnosis of myocardial infarction. It has also been demonstrated that Cardiac Troponin I is targeted for degradation by MuRF1, an E3 ubiquitin ligase that has been linked to muscle atrophy
References
Product Information
Quality LevelMQ300
Applications
ApplicationFull length, recombinant human Cardiac Troponin I. N-terminal c-Myc, GST-tagged. For use in Enzyme Assays. Functions as a substrate in ubiquitination assays.
Key Applications
  • Enzyme Assays
Biological Information
Cascade ComponentSubstrate
Entrez Gene Number
Purification MethodPurified using immobilized metal affinity chromatography.
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Packaging Information
Material Size250 µg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalog Number GTIN
23-055M 04053252444081

Related Products & Applications

Alternative Packsize

Catalog Number Description
23-055 Cardiac Troponin I, 10 µg

Product Families

Ubiquitin Proteasome System: Enzymes and Substrates

Millipore has removed the complexity of Ubiquitination by providing functionally validated enzymes and substrates, making the pathway readily accessible for research and drug discovery.
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Categories

Life Science Research > Drug Discovery and Development > Ubiquitin and Proteasome Screening > Ubiquitination Substrates
Life Science Research > Proteins and Enzymes > Substrate & Control Proteins > Ubiquitination Substrates