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EI6 Chymostatin

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EI6
100 mg  
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Overview

Replacement Information
Description
Catalogue NumberEI6
Brand Family Chemicon®
Trade Name
  • Chemicon
DescriptionChymostatin
OverviewChymostatin. M.W. 604.92

Mixture of types A, B and C. Inhibits Chymotrypsin-like serine proteases including alpha, beta, gamma and delta chymotrtrypsins.

Sequence:

[(S)-1-Carboxy-2-Phenylethyl]-Carbamoyl-a-[2-Iminohexahydro-4(S)-Pyrimidyl]-(S)-Glycyl-X-Phenylalaninal

X: L-Leu (type A), L-Ile (type B), L-Val (type C)

Working concentrations 10-100μM.

Stable for several hours. Soluble in DMSO and glacial acetic acid. Solutions are stable for a month at -20ºC.

5mg/825 microliters in DMSO = 10mM solution.

Dilute 1:100 for 100μM working solution.
References
Product Information
PresentationLyophilized. Dissolve in dimethylsulfoxide (DMSO). After powder is thoroughly dissolved, dilute the DMSO solution with 0.9% NaCl. The concentration of DMSO should be maintained at 10% or higher. Otherwise chymostatin may precipitate from the solution.



Example: Reconstitute 1 mg of chymostatin with 1.65 mL of DMSO. Then add 14.85 mL of 0.9% NaCl. This furnishes a 10-4 M solution. No preservatives added.
Quality LevelMQ100
Applications
Key Applications
  • Inhibits Activity/Function
Biological Information
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsMaintain lyophilized material at -20ºC for up to one year. Store reconstituted product in aliquots at -20ºC for up to 3-4 weeks. Do not thaw and refreeze.
Packaging Information
Material Size100 mg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalog Number GTIN
EI6 04053252619915

Documentation

Chymostatin SDS

Title

Safety Data Sheet (SDS) 

Chymostatin Certificates of Analysis

TitleLot Number
CHYMOSTATIN (Synthetic) - 2385924 2385924
CHYMOSTATIN (Microbial Streptomyces) 2984212
CHYMOSTATIN (Microbial Streptomyces) 2984212A
CHYMOSTATIN (Microbial Streptomyces) 3120600
CHYMOSTATIN (Microbial Streptomyces) - 3199241 3199241
CHYMOSTATIN (Microbial Streptomyces) - 3229401 3229401
CHYMOSTATIN (Microbial Streptomyces) - 3275582 3275582
CHYMOSTATIN (Microbial Streptomyces) - 3316050 3316050
CHYMOSTATIN (Microbial Streptomyces) - 3386496 3386496
CHYMOSTATIN (Microbial Streptomyces) - 3389370 3389370

References

Reference overviewPub Med ID
Chymostatin, a new chymotrypsin inhibitor produced by actinomycetes.
Umezawa, H, et al.
J. Antibiot., 23: 425-7 (1970)  1970

5453321 5453321

Technical Info

Title
Protein Blotting Handbook: 6th Edition