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100247 Citric acid

anhydrous fine-granular EMPROVE® ESSENTIAL Ph Eur,BP,ChP,JP,USP,E 330,FCC

Citric acid MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: 2-Hydroxypropane-1,2,3-tricarboxylic acid, Hydroxytricarballylic acid

CAS #: 77-92-9 EC Number: 201-069-1 Molar Mass: 192.12 g/mol Chemical Formula: (HOOCCH₂)₂C(OH)COOH Hill Formula: C₆H₈O₇ Grade: Ph Eur,BP,ChP,JP,USP,E 330,FCC
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Overview

Replacement Information

Key Specifications Table

CAS #EC NumberHill FormulaChemical FormulaMolar MassGrade Value
77-92-9201-069-1C₆H₈O₇(HOOCCH₂)₂C(OH)COOH192.12 g/molPh Eur,BP,ChP,JP,USP,E 330,FCC

Products

Catalog NumberPackaging Qty/Pack
1002475000 Plastic bottle 5 kg
1.00247.9029 Double PE Sack 25 kg
Description
Catalogue Number100247
Synonyms2-Hydroxypropane-1,2,3-tricarboxylic acid, Hydroxytricarballylic acid
DescriptionCitric acid
References
Product Information
CAS number77-92-9
EC number201-069-1
GradePh Eur,BP,ChP,JP,USP,E 330,FCC
Hill FormulaC₆H₈O₇
Chemical formula(HOOCCH₂)₂C(OH)COOH
Molar Mass192.12 g/mol
HS Code2918 14 00
Structure formula ImageStructure formula Image
Quality LevelMQ500
Applications
Biological Information
Physicochemical Information
Boiling point200 °C (1013 hPa) (decomposition)
Density1.67 g/cm3 (20 °C)
Melting Point153 °C (decomposition)
pH value1.7 (100 g/l, H₂O, 20 °C)
Vapor pressure<0.1 hPa (25 °C)
Bulk density560 kg/m3
Solubility1330 g/l
Dimensions
Materials Information
Toxicological Information
LD 50 oralLD50 Rat 3000 mg/kg
Safety Information according to GHS
Hazard Pictogram(s) Hazard Pictogram(s)
Hazard Statement(s)H319: Causes serious eye irritation.
H335: May cause respiratory irritation.
Precautionary Statement(s)P261: Avoid breathing dust.
P264: Wash skin thoroughly after handling.
P271: Use only outdoors or in a well-ventilated area.
P280: Wear eye protection/ face protection.
P304 + P340 + P312: IF INHALED: Remove person to fresh air and keep comfortable for breathing. Call a POISON CENTER/doctor if you feel unwell.
P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
Signal WordWarning
RTECSGE7350000
Storage class10 - 13 Other liquids and solids
WGKWGK 1 slightly hazardous to water
Safety Information
Categories of dangerirritant
Product Usage Statements
Storage and Shipping Information
StorageStore at +2°C to +30°C.
Packaging Information
Transport Information
Declaration (railroad and road) ADR, RIDKein Gefahrgut
Declaration (transport by air) IATA-DGRNo Dangerous Good
Declaration (transport by sea) IMDG-CodeNo Dangerous Good
Supplemental Information
Specifications
Assay (alkalimetric, calculated on anhydrous substance)99.5 - 100.5 %
Identity (IR-spectrum)passes test
Identity (wet chemistry)passes test
Appearancewhite to almost white, fine-granular powder
Appearance of solution (200 g/l; water)clear (≤ 1.5 NTU) and not more intense in color than reference solution Y₇, BY₇ or GY₇
Chloride (Cl)≤ 5 ppm
Sulfate (SO₄)≤ 50 ppm
Heavy metals (as Pb)≤ 5 ppm
Al (Aluminium)≤ 0.2 ppm
As (Arsenic)≤ 1 ppm
Ca (Calcium)passes test
Hg (Mercury)≤ 1 ppm
Pb (Lead)≤ 0.5 ppm
Oxalates (as C₂H₂O₄)≤ 100 ppm
Oxalate (C₂H₂O₄) (ChP)passes test
Residual solvents (ICH (Q3C))excluded by manufacturing process
Readily carbonisable substancepasses test
Sulfated ash (600 °C)≤ 0.05 %
Water (according to Karl Fischer)≤ 0.5
Bacterial endotoxins< 0.5
Elemental impurity specifications have been set considering ICH Q3D (Guideline for Elemental Impurities). Class 1-3 elements are not likely to be present above the ICH Q3D option 1 limit, unless specified and indicated (*).
Corresponds to Ph. Eur., BP, ChP, JP, USP, E 330, FCC
Conforms to the purity criteria on food additives according to the current European Commission Regulation.
Global Trade Item Number
Catalog Number GTIN
1002475000 04022536003511
1.00247.9029 04022536939766

Documentation

Material Qualification Dossier

TitleVersion
9.0

Quality Management Dossier (Open Access)

Title

Operational Excellence Dossier

Title

Citric acid SDS

Title

Safety Data Sheet (SDS) 

Citric acid Certificates of Analysis

Product Number PackagingSpecificationLot Number
1002475000 Plastic bottlePDF Specification Document
1.00247.9029 Double PE SackPDF Specification Document

Certificates

Title

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Categories

Small Molecule Pharmaceuticals > Formulation > Solid Dosage Form > pH Adjustment
Biopharmaceutical Manufacturing > Formulation > Liquid Dosage > pH Adjustments and Isotonizers
Small Molecule Pharmaceuticals > Formulation > Liquid Dosage Form > Taste Modifiers
Small Molecule Pharmaceuticals > Formulation > Liquid Dosage Form > pH Adjustments and Isotonizers
Biopharmaceutical Manufacturing > Formulation > Liquid Dosage > Taste Modifiers
Small Molecule Pharmaceuticals > Formulation > Solid Dosage Form > Taste Modifiers