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235135 Corticosterone - CAS 50-22-6 - Calbiochem

Corticosteroid hormone synthesized in response to stress.

Corticosterone - CAS 50-22-6 - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: (11β)-11,21-Dihydroxypregn-4-ene-3,20-dione, Reichstein’s substance H

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Overview

Replacement Information

Key Specifications Table

CAS #Empirical Formula
50-22-6C₂₁H₃₀O₄

Products

Catalog NumberPackaging Qty/Pack
235135-1GM Plastic ampoule 1 gm
Description
OverviewCorticosteroid hormone synthesized in response to stress. Binds to and activates mineralocorticoid and glucocorticoid receptors, resulting in altered expression which eventually affects ionic conductances through the membrane. Also induces apoptosis in murine bone marrow.
Catalogue Number235135
Brand Family Calbiochem®
Synonyms(11β)-11,21-Dihydroxypregn-4-ene-3,20-dione, Reichstein’s substance H
References
ReferencesGarvy, B.A., et al. 1993. Immunology 80, 587.
DeKloet, E.R. 1992. Ann. N.Y. Acad. Sci. 663, 357.
Joels, M., and deKloet, E.R. 1992. Trends Neurosci. 15, 25.
Product Information
CAS number50-22-6
ATP CompetitiveN
FormOff-white crystalline powder
Hill FormulaC₂₁H₃₀O₄
Chemical formulaC₂₁H₃₀O₄
ReversibleN
Structure formula ImageStructure formula Image
Quality LevelMQ100
Applications
Biological Information
Primary TargetMineralocorticoid and glucocorticoid receptors
Purity≥95% by HPLC
Physicochemical Information
Cell permeableN
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
RTECSGM7650000
Safety Information
R PhraseR: 62-63

Possible risk of impaired fertility.
Possible risk of harm to the unborn child.
S PhraseS: 22-36

Do not breathe dust.
Wear suitable protective clothing.
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Carcinogenic / Teratogenic
Storage +15°C to +30°C
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalog Number GTIN
235135-1GM 04055977199642

Documentation

Corticosterone - CAS 50-22-6 - Calbiochem SDS

Title

Safety Data Sheet (SDS) 

Corticosterone - CAS 50-22-6 - Calbiochem Certificates of Analysis

TitleLot Number
235135

References

Reference overview
Garvy, B.A., et al. 1993. Immunology 80, 587.
DeKloet, E.R. 1992. Ann. N.Y. Acad. Sci. 663, 357.
Joels, M., and deKloet, E.R. 1992. Trends Neurosci. 15, 25.
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision01-May-2019 JSW
Synonyms(11β)-11,21-Dihydroxypregn-4-ene-3,20-dione, Reichstein’s substance H
DescriptionCorticosteroid hormone synthesized in response to stress. Binds to and activates mineralocorticoid and glucocorticoid receptors, resulting in altered genomic expression. Steroid-induced changes in protein synthesis eventually affect ionic conductances through the membrane. Also induces apoptosis in murine bone marrow.
FormOff-white crystalline powder
CAS number50-22-6
RTECSGM7650000
Chemical formulaC₂₁H₃₀O₄
Structure formulaStructure formula
Purity≥95% by HPLC
SolubilityEthanol (50 mg/ml)
Storage +15°C to +30°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Toxicity Carcinogenic / Teratogenic
Merck USA index14, 2538
ReferencesGarvy, B.A., et al. 1993. Immunology 80, 587.
DeKloet, E.R. 1992. Ann. N.Y. Acad. Sci. 663, 357.
Joels, M., and deKloet, E.R. 1992. Trends Neurosci. 15, 25.