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324788 DAPK Inhibitor - CAS 315694-89-4 - Calbiochem

The DAPK Inhibitor, also referenced under CAS 315694-89-4, controls the biological activity of DAPK.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: (4Z)-4-(3-Pyridylmethylene)-2-styryl-oxazol-5-one, Death-Associated Protein Kinase Inhibitor

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Overview

Replacement Information

Key Specifications Table

CAS #Empirical Formula
315694-89-4C₁₇H₁₂N₂O₂

Products

Catalog NumberPackaging Qty/Pack
324788-10MG Glass bottle 10 mg
Description
OverviewAn oxazalone compound that acts as a potent, ATP-competitive, and highly selective death-associated protein kinase (DAPK) inhibitor (IC50 = 69 and 225 nM against DAPK1 and DAPK3, respectively, with 10 µM ATP), while exhibiting much reduced or no activity against a panel of 48 other kinases even at concentrations as high as 10 µM.
Catalogue Number324788
Brand Family Calbiochem®
Synonyms(4Z)-4-(3-Pyridylmethylene)-2-styryl-oxazol-5-one, Death-Associated Protein Kinase Inhibitor
References
ReferencesOkamoto, M., et al. 2009. J. Med. Chem. 52, 7323.
Product Information
CAS number315694-89-4
FormYellow solid
Hill FormulaC₁₇H₁₂N₂O₂
Chemical formulaC₁₇H₁₂N₂O₂
Quality LevelMQ100
Applications
Biological Information
Purity≥95% by HPLC
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Standard Handling
Storage +2°C to +8°C
Protect from Light Protect from light
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
Packaging Information
Packaged under inert gas Packaged under inert gas
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalog Number GTIN
324788-10MG 04055977216127

Documentation

DAPK Inhibitor - CAS 315694-89-4 - Calbiochem SDS

Title

Safety Data Sheet (SDS) 

DAPK Inhibitor - CAS 315694-89-4 - Calbiochem Certificates of Analysis

TitleLot Number
324788

References

Reference overview
Okamoto, M., et al. 2009. J. Med. Chem. 52, 7323.
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision07-April-2011 RFH
Synonyms(4Z)-4-(3-Pyridylmethylene)-2-styryl-oxazol-5-one, Death-Associated Protein Kinase Inhibitor
DescriptionAn oxazalone compound that acts as a potent, ATP-competitive, and highly selective death-associated protein kinase (DAPK) inhibitor (IC50 = 69 and 225 nM against DAPK1 and DAPK3, respectively, with 10 µM ATP), while exhibiting much reduced or no activity against a panel of 48 other kinases even at concentrations as high as 10 µM.
FormYellow solid
Intert gas (Yes/No) Packaged under inert gas
CAS number315694-89-4
Chemical formulaC₁₇H₁₂N₂O₂
Purity≥95% by HPLC
SolubilityDMSO (25 mg/ml)
Storage Protect from light
+2°C to +8°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
Toxicity Standard Handling
ReferencesOkamoto, M., et al. 2009. J. Med. Chem. 52, 7323.