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344905 FURA 2/AM - CAS 108964-32-5 - Calbiochem

Cell-permeable ester form of FURA 2.

FURA 2/AM - CAS 108964-32-5 - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: 1-[2-(5-Carboxyoxazol-2-yl)-6-aminobenzofuran-5-oxy]-2-(2ʹ-amino-5ʹ-methylphenoxy)-ethane-N,N,NʹNʹ-tetraacetic Acid Pentaacetoxymethyl Ester

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344905
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Overview

Replacement Information

Products

Catalog NumberPackaging Qty/Pack
344905-1MG Plastic ampoule 1 mg
344905-1SET Glass bottle 1 set
Description
OverviewCell-permeable ester form of FURA 2. Note: 1 set = 10 x 100 µg.
PLURONIC® F-127, PROTEIN GRADE® Detergent (Cat. No. 540025, available separately) is a mild, low-toxicity detergent that can aid in the solubilization of FURA 2/AM.
Catalogue Number344905
Brand Family Calbiochem®
Synonyms1-[2-(5-Carboxyoxazol-2-yl)-6-aminobenzofuran-5-oxy]-2-(2ʹ-amino-5ʹ-methylphenoxy)-ethane-N,N,NʹNʹ-tetraacetic Acid Pentaacetoxymethyl Ester
References
ReferencesDavis, M.J., et al. 1992. Am. J. Physiol. 263, H1292.
Rao, G.H., et al. 1992. Biochem. Med. Metab. Biol. 47, 226.
Schwartz, Y., et al. 1992. Endocrinology 131, 772.
Ward, C.A., and Moffat, M.P. 1992. J. Mol. Cell. Cardiol. 24, 937.
Janconi, M.E., et al. 1990. J. Cell Biol. 110, 1555.
Tsien, R.Y. 1980. Biochemistry 19, 2396.
Product Information
CAS number108964-32-5
ATP CompetitiveN
FormYellow solid
Hill FormulaC₄₄H₄₇N₃O₂₄
Chemical formulaC₄₄H₄₇N₃O₂₄
ReversibleN
Structure formula ImageStructure formula Image
Quality LevelMQ100
Applications
Biological Information
Primary TargetRatiometric calcium indicator
Purity≥95% by HPLC.
Physicochemical Information
Cell permeableY
Emission max.
Excitation max.
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Standard Handling
Storage -20°C
Protect from Light Protect from light
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C) under an inert gas. Stock solutions are stable for up to 1 month at -20°C.
Packaging Information
Packaged under inert gas Packaged under inert gas
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalog Number GTIN
344905-1MG 04055977214895
344905-1SET 04055977214901

Documentation

FURA 2/AM - CAS 108964-32-5 - Calbiochem SDS

Title

Safety Data Sheet (SDS) 

FURA 2/AM - CAS 108964-32-5 - Calbiochem Certificates of Analysis

TitleLot Number
344905

References

Reference overview
Davis, M.J., et al. 1992. Am. J. Physiol. 263, H1292.
Rao, G.H., et al. 1992. Biochem. Med. Metab. Biol. 47, 226.
Schwartz, Y., et al. 1992. Endocrinology 131, 772.
Ward, C.A., and Moffat, M.P. 1992. J. Mol. Cell. Cardiol. 24, 937.
Janconi, M.E., et al. 1990. J. Cell Biol. 110, 1555.
Tsien, R.Y. 1980. Biochemistry 19, 2396.

Brochure

Title
Fluorescent Calcium Probes Technical Bulletin
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision27-June-2008 RFH
Synonyms1-[2-(5-Carboxyoxazol-2-yl)-6-aminobenzofuran-5-oxy]-2-(2ʹ-amino-5ʹ-methylphenoxy)-ethane-N,N,NʹNʹ-tetraacetic Acid Pentaacetoxymethyl Ester
DescriptionCell permeant ester form of FURA 2 (Cat. No. 344900). The active dye is rapidly released in the cell by cytoplasmic esterases. Fluorescent calcium chelator (Kd = 224 nM) that offers 30 times greater fluorescence intensity than QUIN 2 (Cat. No. 551826). Can be used as a probe in many cellular systems, including cardiac myocytes, vascular smooth muscle cells, and medullary collecting tubules. Spectral properties in the presence of low calcium concentrations (excitation max.: 362 nm, emission max.: 512 nm) differ from those during high calcium conditions (excitation max.: 335 nm, emission max.: 505 nm). Note: 1 set = 10 x 100 µg.
FormYellow solid
Intert gas (Yes/No) Packaged under inert gas
CAS number108964-32-5
Chemical formulaC₄₄H₄₇N₃O₂₄
Structure formulaStructure formula
Purity≥95% by HPLC.
SolubilityDMSO (10 mg/ml). Further dilute with aqueous buffers just prior to use.
Storage Protect from light
-20°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C) under an inert gas. Stock solutions are stable for up to 1 month at -20°C.
Toxicity Standard Handling
ReferencesDavis, M.J., et al. 1992. Am. J. Physiol. 263, H1292.
Rao, G.H., et al. 1992. Biochem. Med. Metab. Biol. 47, 226.
Schwartz, Y., et al. 1992. Endocrinology 131, 772.
Ward, C.A., and Moffat, M.P. 1992. J. Mol. Cell. Cardiol. 24, 937.
Janconi, M.E., et al. 1990. J. Cell Biol. 110, 1555.
Tsien, R.Y. 1980. Biochemistry 19, 2396.