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344215 Formononetin - CAS 485-72-3 - Calbiochem

Overview

Replacement Information

Key Specifications Table

CAS #Empirical Formula
485-72-3C₁₆H₁₂O₄

Products

Catalog NumberPackaging Qty/Pack
344215-5MG Plastic ampoule 5 mg
Description
OverviewA phytoestrogenic isoflavone found in soy-based foods. Displays potent antioxidant properties and acts as a selective inhibitor of the γ-isoform of alcohol dehydrogenase. Shown to interact with human estrogen receptors with low potency. Induces mammary gland proliferation in mice.
Catalogue Number344215
Brand Family Calbiochem®
Synonyms7-Hydroxy-3-(4ʹ-methoxyphenyl)-4H-benzopyran-4-one
References
ReferencesPool-Zobel, B.L., et al. 2000. Carcinogenesis 21, 1247.
Toda, S., and Shirataki, Y. 1999. Phytother. Res. 13, 163.
Ruiz-Larrea, M.B., et al. 1997. Free Radic. Res. 26, 63.
Keung, W.M. 1995. Biochem. Biophys. Res. Commun. 215, 1137.
Wang, W., et al. 1995. Nutr. Cancer 23, 131.
Miksicek, R.J. 1994. J. Steroid Biochem. Mol. Biol. 49, 153.
Product Information
CAS number485-72-3
ATP CompetitiveN
FormWhite to off-white solid
Hill FormulaC₁₆H₁₂O₄
Chemical formulaC₁₆H₁₂O₄
ReversibleN
Structure formula ImageStructure formula Image
Quality LevelMQ100
Applications
Biological Information
Primary TargetSelective inhibitor of the γ-isoform of alcohol dehydrogenase
Purity≥90% by HPLC
Physicochemical Information
Cell permeableN
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
R PhraseR: 36/37/38

Irritating to eyes, respiratory system and skin.
S PhraseS: 26-36

In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
Wear suitable protective clothing.
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Irritant
Storage -20°C
Protect from Light Protect from light
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C. Do not re-freeze any thawed aliquots.
Packaging Information
Packaged under inert gas Packaged under inert gas
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalog Number GTIN
344215-5MG 04055977215311

Documentation

Formononetin - CAS 485-72-3 - Calbiochem SDS

Title

Safety Data Sheet (SDS) 

Formononetin - CAS 485-72-3 - Calbiochem Certificates of Analysis

TitleLot Number
344215

References

Reference overview
Pool-Zobel, B.L., et al. 2000. Carcinogenesis 21, 1247.
Toda, S., and Shirataki, Y. 1999. Phytother. Res. 13, 163.
Ruiz-Larrea, M.B., et al. 1997. Free Radic. Res. 26, 63.
Keung, W.M. 1995. Biochem. Biophys. Res. Commun. 215, 1137.
Wang, W., et al. 1995. Nutr. Cancer 23, 131.
Miksicek, R.J. 1994. J. Steroid Biochem. Mol. Biol. 49, 153.
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision31-May-2018 JSW
Synonyms7-Hydroxy-3-(4ʹ-methoxyphenyl)-4H-benzopyran-4-one
DescriptionA non-steroidal phytoestrogenic isoflavone found in soy-based food products. Has been shown to interact with human estrogen receptor with relatively low potency. Induces mammary gland proliferation in mice. Inhibits lecithin peroxidation induced by hydroxyl radicals. Also acts as a selective inhibitor of γ-isoform of alcohol dehydrogenase.
FormWhite to off-white solid
Intert gas (Yes/No) Packaged under inert gas
CAS number485-72-3
Chemical formulaC₁₆H₁₂O₄
Structure formulaStructure formula
Purity≥90% by HPLC
SolubilityDMSO (200 mg/ml) or Methanol (2 mg/ml)
Storage Protect from light
-20°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C. Do not re-freeze any thawed aliquots.
Toxicity Irritant
Merck USA index14, 4244
ReferencesPool-Zobel, B.L., et al. 2000. Carcinogenesis 21, 1247.
Toda, S., and Shirataki, Y. 1999. Phytother. Res. 13, 163.
Ruiz-Larrea, M.B., et al. 1997. Free Radic. Res. 26, 63.
Keung, W.M. 1995. Biochem. Biophys. Res. Commun. 215, 1137.
Wang, W., et al. 1995. Nutr. Cancer 23, 131.
Miksicek, R.J. 1994. J. Steroid Biochem. Mol. Biol. 49, 153.