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AP128P Goat Anti-Mouse IgM Antibody, µ chain, HRP conjugate

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AP128P
2 mL  
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Overview

Replacement Information
Description
Catalogue NumberAP128P
Brand Family Chemicon®
Trade Name
  • Chemicon
DescriptionGoat Anti-Mouse IgM Antibody, µ chain, HRP conjugate
Background InformationIgM normally constitutes about 10% of serum immunoglobulins. IgM antibody is prominent in early immune responses to most antigens and predominates in certain antibody responses such as 'natural' blood group antibodies. IgM (with IgD) is the major immunoglobulin expressed on the surface of B cells. The gene for the mu constant region contains four domains separated by short intervening sequences.

Class specific anti immunoglobulin antibodies are useful for: The characterization of malignant B cell proliferations. All but acute lymphocytic leukemias share either surface or intra cytoplasmic Ig with an isotypic restriction, which suggest the monoclonal nature of the cell population. Most of the chronic lymphocytic leukemias, non Hodgkin lymphomas and Burkitt's lymphoma bear surface IgM, whereas plasmocytes from Waldenström's disease bear intracytoplasmic IgM. The other isotypes are less frequently found. On the other hand multiple myelomas are usually of the IgG or IgA type.
References
Product Information
FormatHRP
HS Code3002 15 90
PresentationFreeze dried powder, made from liquid containing 0.01M phosphate buffered saline, 0.25M sodium chloride, 15 mg/mL bovine serum with no preservatives. Reconstitute in 2mL deionized water, centrifuge if not clear. Prepare a working dilution fresh for each day.
Quality LevelMQ100
Applications
ApplicationThis Goat anti-Mouse IgM Antibody, μ chain, HRP conjugate is validated for use in ELISA, WB for the detection of Mouse IgM.
Key Applications
  • ELISA
  • Western Blotting
Biological Information
Concentration0.8-1.0 mg/mL
HostGoat
SpecificityBased on immunoelectrophoresis, the antibody reacts with the heavy chain portion of IgM. No reactivity with IgG or non-immunoglobulin serum proteins was detected, but cross reactivity with IgM from other species may be detected.
Species Reactivity
  • Mouse
Antibody TypePolyclonal Antibody
Purification MethodImmunoAffinity Purified
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsMaintain lyophilized product at 2-8°C for up to 12 months. After reconstitution the product is stable for several weeks at 2-8°C as an undiluted liquid. For extended storage after reconstitution, add an equal volume of glycerol to make a final concentration of 50% glycerol followed by storage at -20°C in undiluted aliquots for up to 12 months. Please note the concentration of protein (and buffer salts) will decrease to one-half of the original after the addition of glycerol. Avoid repeated freeze/thaw cycles.
Packaging Information
Material Size2 mL
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalog Number GTIN
AP128P 04053252476730

Documentation

Goat Anti-Mouse IgM Antibody, µ chain, HRP conjugate SDS

Title

Safety Data Sheet (SDS) 

Goat Anti-Mouse IgM Antibody, µ chain, HRP conjugate Certificates of Analysis

TitleLot Number
GOAT ANTI-MOUSE IgM (#956;#61472; chain specific) HORSERADISH PEROXIDASE CONJUGATED, AFFINITY PURIFIED SECONDARY ANTIBODY - 2032677 2032677
GOAT ANTI-MOUSE IgM (m chain specific) HORSERADISH PEROXIDASE CONJUGATED, AFFINITY PURIFIED SECONDARY ANTIBODY - 1997374 1997374
GOAT ANTI-MOUSE IgM (m chain specific) HORSERADISH PEROXIDASE CONJUGATED, AFFINITY PURIFIED SECONDARY ANTIBODY - 2049784 2049784
GOAT ANTI-MOUSE IgM (m chain specific) HORSERADISH PEROXIDASE CONJUGATED, AFFINITY PURIFIED SECONDARY ANTIBODY - 2090434 2090434
GOAT ANTI-MOUSE IgM (m chain specific) HORSERADISH PEROXIDASE CONJUGATED, AFFINITY PURIFIED SECONDARY ANTIBODY - 2187331 2187331
GOAT ANTI-MOUSE IgM (m chain specific) HORSERADISH PEROXIDASE CONJUGATED, AFFINITY PURIFIED SECONDARY ANTIBODY - 2290937 2290937
GOAT ANTI-MOUSE IgM (u chain specific) HORSERADISH PEROXIDASE CONJUGATED, AFFINITY PURIFIED SECONDARY ANTIBODY 2907674
GOAT ANTI-MOUSE IgM (u chain specific) HORSERADISH PEROXIDASE CONJUGATED, AFFINITY PURIFIED SECONDARY ANTIBODY 2943391
GOAT ANTI-MOUSE IgM (u chain specific) HORSERADISH PEROXIDASE CONJUGATED, AFFINITY PURIFIED SECONDARY ANTIBODY 2886841
GOAT ANTI-MOUSE IgM (µ chain specific) HORSERADISH PEROXIDASE CONJUGATED, AFFINITY PURIFIED SECONDARY ANTIBODY 2942630

References

Reference overviewPub Med ID
Modulation of cellular adhesion by glycoengineering.
Dafik, L; d'Alarcao, M; Kumar, K
Journal of medicinal chemistry  53  4277-84  2010

Show Abstract Full Text Article
20438083 20438083