370677 Sigma-AldrichGuanosine 3ʹ,5ʹ-cyclic Monophosphorothioate, 8-(4-Chlorophenylthio)-, Rp-Isomer, Triethylammonium Salt - Calbiochem
A potent, cell-permeable, and metabolically-stable inhibitor of protein kinase G Iα, Iβ, and type II.
More>> A potent, cell-permeable, and metabolically-stable inhibitor of protein kinase G Iα, Iβ, and type II. Less<<MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Synonyms: Rp-8-pCPT-cGMPS, TEA, PKG Inhibitor III
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Overview
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Key Specifications Table
| Empirical Formula |
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| C₁₆H₁₅ClN₅O₆PS₂ · C₆H₁₅N |
Products
| Catalog Number | Packaging | Qty/Pack | |
|---|---|---|---|
| 370677-1UMOL | Plastic ampoule | 1 umol |
| Description | |
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| Overview | A potent, cell-permeable, and metabolically-stable inhibitor of protein kinase G Iα, Iβ, and type II. Significantly more lipophilic and membrane-permeable than Rp-cGMPS or Rp-8-Br-cGMPS (Cat. No. 370674). Note: 1 µmol = 0.61 mg. |
| Catalogue Number | 370677 |
| Brand Family | Calbiochem® |
| Synonyms | Rp-8-pCPT-cGMPS, TEA, PKG Inhibitor III |
| Product Information | |
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| ATP Competitive | N |
| Declaration | Sold under license of U.S. Patent 5,625,056, Patents DE 3,802,865.4, and DE 4,217,679 issued to BIOLOG LSI. |
| Form | Lyophilized |
| Hill Formula | C₁₆H₁₅ClN₅O₆PS₂ · C₆H₁₅N |
| Chemical formula | C₁₆H₁₅ClN₅O₆PS₂ · C₆H₁₅N |
| Hygroscopic | Hygroscopic |
| Reversible | N |
| Structure formula Image | |
| Quality Level | MQ100 |
| Applications |
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| Biological Information | |
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| Primary Target | PKG1α |
| Purity | ≥99% by HPLC |
| Physicochemical Information | |
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| Cell permeable | Y |
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| Toxicological Information |
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| Safety Information according to GHS |
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| Safety Information |
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| Product Usage Statements |
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| Specifications |
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| Global Trade Item Number | |
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| Catalog Number | GTIN |
| 370677-1UMOL | 04055977191707 |
Documentation
Guanosine 3ʹ,5ʹ-cyclic Monophosphorothioate, 8-(4-Chlorophenylthio)-, Rp-Isomer, Triethylammonium Salt - Calbiochem SDS
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Guanosine 3ʹ,5ʹ-cyclic Monophosphorothioate, 8-(4-Chlorophenylthio)-, Rp-Isomer, Triethylammonium Salt - Calbiochem Certificates of Analysis
| Title | Lot Number |
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| 370677 |
References
| Reference overview |
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| Abd Alla, S., et al. 1996. Eur. J. Biochem. 241, 498. Lee, S.J., et al. 1996. Dev. Biol. 180, 324. Van Uffelen, B.E., et al. 1996. J. Leukoc. Biol. 60, 94. Willmott, N., et al. 1996. J. Biol. Chem. 271, 3699. Butt, E., et al. 1994. Eur. J. Pharmacol. 269, 265. |