Millipore Sigma Vibrant Logo
Attention: We have moved. EMD Millipore products are no longer available for purchase on emdmillipore.com.Learn More

GF418-MG HumanKine® IL-1 beta, Human Recombinant Xeno-Free

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
UniProt Number: P01584
GF418-MG
1mg  
Purchase on Sigma-Aldrich

Special Offers

Overview

Replacement Information

Special Offers

Bulk Size Quantities of HumanKine Growth Factors are Available.
Click Here for more information.

Key Specifications Table

SourcePurity
HumanKine growth factors are expressed in a proprietary human 293 protein expression system and are manufactured without the use of any animal products and are considered Xeno-Free.Product is endotoxin free (<0.1 ng/μg of protein (<1 EU/μg) and greater than 95% pure by SDS-PAGE.
Description
Catalogue NumberGF418-MG
Trade Name
  • HumanKine®
DescriptionHumanKine® IL-1 beta, Human Recombinant Xeno-Free
Alternate Names
  • IL1B
  • Catabolin
  • pro-interleukin-1-beta
Background InformationInterleukin-1 (IL-1) is a cytokine that is thought to be connected to neurodegeneration and in central nervous system-mediated defense reactions to inflammation. Interleukin-1 beta (IL-1B) maintains mitogen-induced proliferation, IL-2 production and expression of IL-2R. IL-1 beta also seems to have the ability to boost the number of cells that move into the G1 phase of the cell cycle. IL-1 beta also has the capacity to stimulate apoptosis on normal human fetal membranes. IL-1 beta may play an important role in inflammation regulating cytokine networks.
References
Product Information
Formulation
PresentationProduct is presented in PBS and filtered through a 0.2 micron filter before lyophilization.
Quality LevelMQ100
Applications
Biological Information
PurityProduct is endotoxin free (<0.1 ng/μg of protein (<1 EU/μg) and greater than 95% pure by SDS-PAGE.
SourceHumanKine growth factors are expressed in a proprietary human 293 protein expression system and are manufactured without the use of any animal products and are considered Xeno-Free.
UniProt Number
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceBioactivity assay: Determined by the dose-dependent stimulation of the proliferation of mouse D10S cells. ED50 is typically 0.02-0.08 ng/ml.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStore at -20°C for up to 4 months from date of receipt. Further dilutions should be made into appropriate buffer or medium to which protein has been added.
Packaging Information
Material Size1mg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalog Number GTIN
GF418-MG 04053252961625