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GF328 IL-17,
Human Recombinant Animal Free

IL-17,
Human Recombinant Animal Free MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
UniProt Number: Q16552
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GF328
25µg  
Purchase on Sigma-Aldrich

Overview

Replacement Information

Key Specifications Table

SourcePurity
Protein is expressed in E.coli.
The protein is manufactured without the use of any animal products/reagents and is considered Animal-Free and can be used in protocols where possible transmisson of animal viruses and contamination must be avoided.		Product endotoxin level is <0.1 ng/μg of protein (<1 EU/μg).
Description
Catalogue NumberGF328
DescriptionIL-17,
Human Recombinant Animal Free
Alternate Names
  • Interleukin-17
  • IL17
  • IL17a
Background InformationThe originally described IL-17 protein, now known as IL-17A, is a homodimer of two 136 amino acid chains, secreted by activated T-cells that act on stromal cells to induce production of proinflammatory and hematopoietic bioactive molecules. Today, IL-17 represents a family of structurally-related cytokines that share a highly conserved C-terminal region but differ from one another in their N-terminal regions and in their distinct biological roles. The six known members of this family, IL-17A through IL-17F, are secreted as homodimers. IL-17A exhibits cross-species bioactivity between human and murine cells.
Recombinant human IL-17A is a 31.3 kDa disulfide-linked homodimer of two 137 amino acid polypeptide chains.
References
Product Information
PresentationProduct is presented without additives and is filtered through a 0.2 micron filter before lyophilization.
Quality LevelMQ100
Applications
Biological Information
PurityProduct endotoxin level is <0.1 ng/μg of protein (<1 EU/μg).
SourceProtein is expressed in E.coli.
The protein is manufactured without the use of any animal products/reagents and is considered Animal-Free and can be used in protocols where possible transmisson of animal viruses and contamination must be avoided.
UniProt Number
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceAssay #1: Determined by the dosedependent induction of IL-6 in primary human foreskin fibroblast. The expected ED50 is ≤ 2.0 ng/ml, corresponding to a specific activity of ≥ 5 x 10^5 units/mg.
Assay #2: Measured by its ability to induce IL-6 production by NHDF cells.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStore at -20°C for up to 4 months from date of receipt Centrifuge the vial prior to opening.
Reconstitute in water to a concentration of 0.1-1.0 mg/ml. Do not vortex. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein and store in working aliquots at -20°C.
Packaging Information
Material Size25µg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalog Number GTIN
GF328 04053252978913

Documentation

IL-17,
Human Recombinant Animal Free SDS

Title

Safety Data Sheet (SDS) 

IL-17,
Human Recombinant Animal Free Certificates of Analysis

TitleLot Number
IL-17, Human Recombinant Animal Free - Q2442614 Q2442614
IL-17, Human Recombinant Animal Free - 3279693 3279693
IL-17, Human Recombinant Animal Free - 3532078 3532078
IL-17, Human Recombinant Animal Free - 3743853 3743853
IL-17, Human Recombinant Animal Free - 3755333 3755333
IL-17, Human Recombinant Animal Free - 3894061 3894061
IL-17, Human Recombinant Animal Free - 4002907 4002907
IL-17, Human Recombinant Animal Free Recombinant Protein 2951392

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Product Families

Cytokines and Growth Factors

EMD Millipore offers a comprehensive range of highly purified bioactive cytokines and growth factors for use in human, mouse, and rat cell culture, stem cell differentiation and ELISA studies.
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Categories

Life Science Research > Proteins and Enzymes > Cytokines & Growth Factors
Life Science Research > Cell Culture and Systems > Cell Culture Media and Supplements > Cell Culture Supplements > Cytokines & Growth Factors