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530748 InSolution™ SRT1720, HCl - Calbiochem

A 25 mM (10 mg/650 µl) sterile-filtered solution of SRT1720, HCl in DMSO.

InSolution™ SRT1720, HCl - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: N-(2-(3-(1-Piperazinylmethyl)imidazo[2,1-b]thiazol-6-yl)phenyl)-2-quinolinecarboxamide, 4HCl;, Histone Acetyltransferase Inhibitor XI, p300/CBP Inhibitor IX, SRT1720, HCl InSolution™, HAT Inhibitor XI, SIRT3 Inhibitor II, Sirtuin-3 Inhibitor, SRT1720, HCl

Primary Target: SIRT3
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Overview

Replacement Information

Key Specifications Table

Empirical Formula
C₂₅H₂₃N₇OS • xHCl

Products

Catalog NumberPackaging Qty/Pack
5.30748.0001 Glass bottle 10 mg
Description
OverviewAn enhanced aqueous soluble version of SRT1720 (Cat. No. 567860).

Please note that the molecular weight for this compound is batch-specific due to variable water content.
Catalogue Number530748
Brand Family Calbiochem®
SynonymsN-(2-(3-(1-Piperazinylmethyl)imidazo[2,1-b]thiazol-6-yl)phenyl)-2-quinolinecarboxamide, 4HCl;, Histone Acetyltransferase Inhibitor XI, p300/CBP Inhibitor IX, SRT1720, HCl InSolution™, HAT Inhibitor XI, SIRT3 Inhibitor II, Sirtuin-3 Inhibitor, SRT1720, HCl
References
ReferencesBaur, J.A., et al. 2012. Nat. Rev. Drug Discov. 11, 443.
Minor, R.K., et al. 2011. Sci. Rep. 1, 70.
Huber, J.L., et al. 2010. Future Med. Chem. 2, 1751.
Pacholec, M., et al. 2010. J. Biol. Chem. 285, 8340.
Jin, L., et al. 2009. Protein Sci. 18, 514.
Feige, J.N., et al. 2008. Cell Metab. 8, 347.
Milne, J.C., et al. 2007. Nature 450, 712.
Product Information
FormLiquid
FormulationA 25 mM (10 mg/650 µl) sterile-filtered solution of SRT1720, HCl (Cat. No. 567860) in DMSO.
Hill FormulaC₂₅H₂₃N₇OS • xHCl
Chemical formulaC₂₅H₂₃N₇OS • xHCl
Hygroscopic Hygroscopic
ReversibleY
Quality LevelMQ100
Applications
Biological Information
Primary TargetSIRT3
Secondary targetp300 HAT
Purity≥98% by HPLC
Physicochemical Information
Cell permeableY
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Dry Ice Only
Toxicity Standard Handling
Storage ≤ -70°C
Protect from Light Protect from light
Hygroscopic Hygroscopic
Avoid freeze/thaw Avoid freeze/thaw
Do not freeze Ok to freeze
Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C). Aliquots are stable for up to 6 months at -20°C.
Packaging Information
Packaged under inert gas Packaged under inert gas
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalog Number GTIN
5.30748.0001 04055977242959

Documentation

InSolution™ SRT1720, HCl - Calbiochem SDS

Title

Safety Data Sheet (SDS) 

References

Reference overview
Baur, J.A., et al. 2012. Nat. Rev. Drug Discov. 11, 443.
Minor, R.K., et al. 2011. Sci. Rep. 1, 70.
Huber, J.L., et al. 2010. Future Med. Chem. 2, 1751.
Pacholec, M., et al. 2010. J. Biol. Chem. 285, 8340.
Jin, L., et al. 2009. Protein Sci. 18, 514.
Feige, J.N., et al. 2008. Cell Metab. 8, 347.
Milne, J.C., et al. 2007. Nature 450, 712.
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision27-June-2014 JSW
SynonymsN-(2-(3-(1-Piperazinylmethyl)imidazo[2,1-b]thiazol-6-yl)phenyl)-2-quinolinecarboxamide, 4HCl;, Histone Acetyltransferase Inhibitor XI, p300/CBP Inhibitor IX, SRT1720, HCl InSolution™, HAT Inhibitor XI, SIRT3 Inhibitor II, Sirtuin-3 Inhibitor, SRT1720, HCl
DescriptionAn enhanced aqueous soluble version of SRT1720 (Cat. No. 567860).
FormLiquid
FormulationA 25 mM (10 mg/650 µl) sterile-filtered solution of SRT1720, HCl (Cat. No. 567860) in DMSO.
Intert gas (Yes/No) Packaged under inert gas
Chemical formulaC₂₅H₂₃N₇OS • xHCl
Purity≥98% by HPLC
Storage Protect from light
Avoid freeze/thaw
≤ -70°C
Hygroscopic
Do Not Freeze Ok to freeze
Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C). Aliquots are stable for up to 6 months at -20°C.
Toxicity Standard Handling
ReferencesBaur, J.A., et al. 2012. Nat. Rev. Drug Discov. 11, 443.
Minor, R.K., et al. 2011. Sci. Rep. 1, 70.
Huber, J.L., et al. 2010. Future Med. Chem. 2, 1751.
Pacholec, M., et al. 2010. J. Biol. Chem. 285, 8340.
Jin, L., et al. 2009. Protein Sci. 18, 514.
Feige, J.N., et al. 2008. Cell Metab. 8, 347.
Milne, J.C., et al. 2007. Nature 450, 712.