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509721 InSolution™ Vitamin D3, 1α, 25-Dihydroxy- - Calbiochem

A 1 mM (50 ug/112 µL) solution of Vitamin D3, 1α, 25-Dihydroxy- in DMSO

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: 1,25-(OH)₂-D₃

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Overview

Replacement Information

Key Specifications Table

Empirical Formula
C₂₇H₄₄O₃

Products

Catalog NumberPackaging Qty/Pack
5.09721.0001 Glass bottle 50 μg
Description
Catalogue Number509721
Brand Family Calbiochem®
Synonyms1,25-(OH)₂-D₃
References
ReferencesSemizarov, D., et al. 1998. Proc. Natl. Acad. Sci. USA 95, 15412.
Hannun, Y.A. 1994. J. Biol. Chem. 269, 3125.
Mathieu, C., et al. 1994. Diabetologica 37, 552.
Thomasset, M. 1994. Pathol. Biol. 42, 163.
Horton, W.E., Jr., et al. 1991. J. Biol. Chem. 266, 24804.
Larsen, C.G., et al. 1991. Biochem. Biophys. Res. Commun. 176, 1020.
Thavarajah, M., et al. 1991. Biochem. Biophys. Res. Commun. 176, 1189.
Wakasugi, M., et al. 1991. Prostaglandins 42, 127.
Matsumoto, K., et al. 1990. Biochem. Biophys. Res. Commun. 166, 916.
Simpson, R.U., et al. 1989. J. Biol. Chem. 264, 19710.
DeLuca, H.F., and Schnoes, H.K. 1983. Annu. Rev. Biochem. 52, 411.
Product Information
FormLiquid
FormulationA 1 mM (50 ug/112 µL) solution of Vitamin D3, 1α, 25-Dihydroxy- (Cat. No. 679101) in DMSO.
Hill FormulaC₂₇H₄₄O₃
Chemical formulaC₂₇H₄₄O₃
Hygroscopic Hygroscopic
Quality LevelMQ200
Applications
Biological Information
Primary Targetvitamin D receptor
Purity≥99% by HPLC
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Dry Ice Only
Toxicity Standard Handling
Storage ≤ -70°C
Protect from Light Protect from light
Hygroscopic Hygroscopic
Avoid freeze/thaw Avoid freeze/thaw
Do not freeze Ok to freeze
Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C). Aliquots are stable for up to 6 months at -20°C.
Packaging Information
Packaged under inert gas Packaged under inert gas
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalog Number GTIN
5.09721.0001 04055977241105

Documentation

InSolution™ Vitamin D3, 1α, 25-Dihydroxy- - Calbiochem SDS

Title

Safety Data Sheet (SDS) 

References

Reference overview
Semizarov, D., et al. 1998. Proc. Natl. Acad. Sci. USA 95, 15412.
Hannun, Y.A. 1994. J. Biol. Chem. 269, 3125.
Mathieu, C., et al. 1994. Diabetologica 37, 552.
Thomasset, M. 1994. Pathol. Biol. 42, 163.
Horton, W.E., Jr., et al. 1991. J. Biol. Chem. 266, 24804.
Larsen, C.G., et al. 1991. Biochem. Biophys. Res. Commun. 176, 1020.
Thavarajah, M., et al. 1991. Biochem. Biophys. Res. Commun. 176, 1189.
Wakasugi, M., et al. 1991. Prostaglandins 42, 127.
Matsumoto, K., et al. 1990. Biochem. Biophys. Res. Commun. 166, 916.
Simpson, R.U., et al. 1989. J. Biol. Chem. 264, 19710.
DeLuca, H.F., and Schnoes, H.K. 1983. Annu. Rev. Biochem. 52, 411.
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision18-April-2014 JSW
Synonyms1,25-(OH)₂-D₃
DescriptionActive hormonal form of vitamin D, formed by the renal 1-hydroxylation of 25-(OH)D3. Has immunomodulatory properties in vitro and in vivo. Prevents the development of clinical diabetes in NOD mice, which are an animal model of human autoimmune diabetes. Induces reversible hydrolysis of the sphingomyelin cycle and generates ceramide. Stimulates intestinal Ca2+ and phosphate transport and mobilizes Ca2+ from bone. Involved in cellular differentiation, carcinogenesis, and insulin secretion.
FormLiquid
FormulationA 1 mM (50 ug/112 µL) solution of Vitamin D3, 1α, 25-Dihydroxy- (Cat. No. 679101) in DMSO.
Intert gas (Yes/No) Packaged under inert gas
Chemical formulaC₂₇H₄₄O₃
Purity≥99% by HPLC
Storage Protect from light
Avoid freeze/thaw
≤ -70°C
Hygroscopic
Do Not Freeze Ok to freeze
Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C). Aliquots are stable for up to 6 months at -20°C.
Toxicity Standard Handling
ReferencesSemizarov, D., et al. 1998. Proc. Natl. Acad. Sci. USA 95, 15412.
Hannun, Y.A. 1994. J. Biol. Chem. 269, 3125.
Mathieu, C., et al. 1994. Diabetologica 37, 552.
Thomasset, M. 1994. Pathol. Biol. 42, 163.
Horton, W.E., Jr., et al. 1991. J. Biol. Chem. 266, 24804.
Larsen, C.G., et al. 1991. Biochem. Biophys. Res. Commun. 176, 1020.
Thavarajah, M., et al. 1991. Biochem. Biophys. Res. Commun. 176, 1189.
Wakasugi, M., et al. 1991. Prostaglandins 42, 127.
Matsumoto, K., et al. 1990. Biochem. Biophys. Res. Commun. 166, 916.
Simpson, R.U., et al. 1989. J. Biol. Chem. 264, 19710.
DeLuca, H.F., and Schnoes, H.K. 1983. Annu. Rev. Biochem. 52, 411.