200488 Sigma-AldrichInSolution™Bestatin, Hydrochloride - Calbiochem
A metalloprotease inhibitor. Reversibly binds to cell surfaces and competitively inhibits surface aminopeptidases, notably aminopeptidase B and leucine aminopeptidase.
More>> A metalloprotease inhibitor. Reversibly binds to cell surfaces and competitively inhibits surface aminopeptidases, notably aminopeptidase B and leucine aminopeptidase. Less<<MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Synonyms: [(2S,3R)-3-Amino-2-hydroxy-4-phenylbutanoyl]-Leu, HCl
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Overview
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Key Specifications Table
| Empirical Formula |
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| C₁₆H₂₄N₂O₄ • HCl |
Products
| Catalog Number | Packaging | Qty/Pack | |
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| 200488-10MG | Glass bottle | 10 mg |
| Description | |
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| Overview | A metalloprotease inhibitor. Reversibly binds to cell surfaces and competitively inhibits surface aminopeptidases, notably aminopeptidase B and leucine aminopeptidase. Also acts as a potent aminopeptidase N inhibitor. Activates macrophages and T lymphocytes. Has anti-tumor properties. Effective at a concentration of 1-10 µM. The solid form of this compound (Cat. No. 200484) is also available. |
| Catalogue Number | 200488 |
| Brand Family | Calbiochem® |
| Synonyms | [(2S,3R)-3-Amino-2-hydroxy-4-phenylbutanoyl]-Leu, HCl |
| Product Information | |
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| Form | Liquid |
| Formulation | Supplied as a 50 mM (10 mg/580 µL) solution of Bestatatin, HCl in H₂O. |
| Hill Formula | C₁₆H₂₄N₂O₄ • HCl |
| Reversible | Y |
| Structure formula Image | |
| Quality Level | MQ100 |
| Applications |
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| Biological Information | |
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| Primary Target | Metalloproteases |
| Purity | ≥98% by HPLC |
| Physicochemical Information | |
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| Cell permeable | N |
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| Materials Information |
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| Toxicological Information |
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| Safety Information according to GHS |
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| Safety Information |
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| Product Usage Statements |
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| Packaging Information | |
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| Packaged under inert gas | Packaged under inert gas |
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| Specifications |
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| Global Trade Item Number | |
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| Catalog Number | GTIN |
| 200488-10MG | 04055977221510 |
Documentation
InSolution™Bestatin, Hydrochloride - Calbiochem SDS
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InSolution™Bestatin, Hydrochloride - Calbiochem Certificates of Analysis
| Title | Lot Number |
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| 200488 |
References
| Reference overview |
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| Merck Index: 14, 9842. Inoue, T., et al. 1994. J. Clin. Endocrinol. Metab. 79, 171. Taylor, A., et al. 1993. Biochemistry 32, 784. Ishida, J.I., et al. 1984. J. Chromatogr. 305, 381. Umezawa, H. 1982. Annu. Rev. Microbiol. 36, 75. |
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Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.
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