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107430 L-Proline

Overview

Replacement Information

Key Specifications Table

CAS #EC NumberHill FormulaMolar MassGrade Value
147-85-3205-702-2C₅H₉NO₂115.13 g/molPh Eur,JP,USP

Products

Catalog NumberPackaging Qty/Pack
1074301000 Plastic bottle 1 kg
1074309010 Plastic drum 10 kg
Description
Catalogue Number107430
SynonymsPro
References
Product Information
CAS number147-85-3
EC number205-702-2
GradePh Eur,JP,USP
Hill FormulaC₅H₉NO₂
Molar Mass115.13 g/mol
HS Code2933 99 19
Structure formula ImageStructure formula Image
Quality LevelMQ500
Applications
Biological Information
Physicochemical Information
Density1.4 g/cm3 (45 °C)
Melting Point221 °C (decomposition)
pH value5 - 7 (100 g/l, H₂O, 20 °C)
Bulk density500 kg/m3
Solubility1500 g/l
Dimensions
Materials Information
Toxicological Information
LD 50 oralLD50 Rat > 5110 mg/kg
Safety Information according to GHS
RTECSTW3584000
Storage class10 - 13 Other liquids and solids
WGKWGK 1 slightly hazardous to water
Disposal3
Relatively unreactive organic reagents should be collected in container A. If halogenated, they should be collected in container B. For solid residues use container C.
Safety Information
Product Usage Statements
Storage and Shipping Information
StorageStore at +2°C to +30°C.
Packaging Information
Transport Information
Supplemental Information
Specifications
Assay (perchloric acid titration, calculated on dried substance)99.0 - 101.0 %
Identity (IR-spectrum)passes test
Identity (specific rotation)passes test
Appearancewhite or almost white, crystalline powder or colorless crystals
Appearance of solution (50 g/l; water)clear and colorless
Appearance of solution (100 g/l, water)clear and colorless
pH (100 g/l, CO₂-free water)5.9 - 6.9
Spec. rotation (α 20/D, 40 g/l, water, calc. on dried substance)-84.0 to -86.0
Spec. rotation (α 25/D, 40 g/l, water, calc. on dried substance)-84.3 to -86.3
Chloride (Cl)≤ 200 ppm
Sulfate (SO₄)≤ 200 ppm
Heavy metals (as Pb)≤ 10 ppm
Fe (Iron)≤ 10 ppm
Mn (Manganese)≤ 25 ppm
Zn (Zinc)≤ 130 ppm
Related Compounds, total (TLC)≤ 0.5 %
Ninhydrin-positive substances (LC) (any ninhydrin-positive impurity)≤ 0.2 %
Ninhydrin-positive substances (LC) (ammonium (570 nm))≤ 0.02 %
Ninhydrin-positive substances (LC) (total impurities)≤ 0.5 %
Related substances (LC)≤ 0.1 %
Residual solvents (ICH Q3C)excluded by manufacturing process
Sulfated ash (600 °C)≤ 0.1 %
Loss on Drying (105 °C)≤ 0.3 %
Bacterial endotoxins≤ 5 I.U./g
Total aerobic microbial count (TAMC)≤ 10²
Total combined yeasts/moulds count (TYMC)≤ 10²
Elemental impurity specifications have been set considering ICH Q3D (Guideline for Elemental Impurities). Class 1-3 elements are not likely to be present above the ICH Q3D option 1 limit, unless specified and indicated (*).
Corresponds to Ph. Eur., JP, USP.
Global Trade Item Number
Catalog Number GTIN
1074301000 04022536906928
1074309010 04022536906935

Documentation

Material Qualification Dossier

TitleVersion
9.0

Quality Management Dossier (Open Access)

Title

Operational Excellence Dossier

Title

L-Proline SDS

Title

Safety Data Sheet (SDS) 

L-Proline Certificates of Analysis

Product Number PackagingSpecificationLot Number
1074301000 Plastic bottlePDF Specification Document
1074309010 Plastic drumPDF Specification Document

Certificates

Title

Brochure

Title
Amino Acids