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107647 L-Serine

Overview

Replacement Information

Key Specifications Table

CAS #EC NumberHill FormulaMolar MassGrade Value
56-45-1200-274-3C₃H₇NO₃105.09 g/molPh Eur,JP,USP

Products

Catalog NumberPackaging Qty/Pack
1076471000 Plastic bottle 1 kg
1076479010 Plastic drum 10 kg
Description
Catalogue Number107647
Synonyms3-Hydroxy-L-alanine, Ser
References
Product Information
CAS number56-45-1
EC number200-274-3
GradePh Eur,JP,USP
Hill FormulaC₃H₇NO₃
Molar Mass105.09 g/mol
HS Code2922 50 00
Structure formula ImageStructure formula Image
Quality LevelMQ500
Applications
Biological Information
Physicochemical Information
Density1.6 g/cm3 (22 °C)
Melting Point222 °C decomposes
pH value5 - 6 (100 g/l, H₂O, 20 °C)
Bulk density570 kg/m3
Solubility360 g/l
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
RTECSVT8100000
Storage class10 - 13 Other liquids and solids
WGKWGK 1 slightly hazardous to water
Disposal3
Relatively unreactive organic reagents should be collected in container A. If halogenated, they should be collected in container B. For solid residues use container C.
Safety Information
Product Usage Statements
Storage and Shipping Information
StorageStore at +2°C to +30°C.
Packaging Information
Transport Information
Supplemental Information
Specifications
Assay (perchloric acid titration, calculated on dried substance)98.5 - 101.0 %
Identity (IR-spectrum)passes test
Identity (specific rotation)passes test
Appearancewhite to almost white or colorless, needle-shaped crystals
Appearance of solution (50 g/l; water)clear and not more intense in color than reference solution BY₆
Appearance of solution (100 g/l, water)clear and colorless
Spec. rotation (α 20/D, 100 g/l, hydrochloric acid 2 mol/l, calc. on dried substance)+14.0 to +16.0
Spec. rotation (α 20/D, 100 g/l, hydrochloric acid 2 mol/l, previously dried substance)+14.0 to +16.0
Spec. rotation (α 25/D, 100 g/l, hydrochloric acid 2 mol/l, calc. on dried substance)+14.0 to +15.6
pH (100 g/l, CO₂-free water)5.2 - 6.2
Chloride (Cl)≤ 200 ppm
Sulfate (SO₄)≤ 200 ppm
Heavy metals (as Pb)≤ 10 ppm
Co (Cobalt)≤ 0.5 ppm
Cu(Copper)≤ 25 ppm
Fe (Iron)≤ 10 ppm
Mn (Manganese)≤ 25 ppm
Mo (Molybdenum)≤ 2.5 ppm
Zn (Zinc)≤ 130 ppm
Related substances (TLC)passes test
Related Compounds, total (TLC)≤ 0.5 %
Ninhydrin-positive substances (LC) (any ninhydrin-positive impurity)≤ 0.2 %
Ninhydrin-positive substances (LC) (ammonium (570 nm))≤ 0.02 %
Ninhydrin-positive substances (LC) (total impurities)≤ 0.5 %
Methanol (HS-GC)≤ 3000 ppm
Other residual solvents (ICH Q3C)excluded by manufacturing process
Sulfated ash (600 °C)≤ 0.1 %
Loss on drying (105 °C; 3 h)≤ 0.2 %
Bacterial endotoxins≤ 2.0 I.U./g
Total aerobic microbial count (TAMC)≤ 10²
Total combined yeasts/moulds count (TYMC)≤ 10²
Elemental impurity specifications have been set considering ICH Q3D (Guideline for Elemental Impurities). Class 1-3 elements are not likely to be present above the ICH Q3D option 1 limit, unless specified and indicated (*).
Corresponds to Ph. Eur., JP, USP.
Global Trade Item Number
Catalog Number GTIN
1076471000 04022536906959
1076479010 04022536906966

Documentation

Material Qualification Dossier

TitleVersion
8.1

Quality Management Dossier (Open Access)

Title

Operational Excellence Dossier

Title

L-Serine SDS

Title

Safety Data Sheet (SDS) 

L-Serine Certificates of Analysis

Product Number PackagingSpecificationLot Number
1076471000 Plastic bottlePDF Specification Document
1076479010 Plastic drumPDF Specification Document

Certificates

Title

Brochure

Title
Amino Acids