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Lifegard™ Cartridge Filters

Superior filters for the clarification and prefiltration of viscous biological fluids when high contaminant holding capacity is required More

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AP15 and AP20 · Code 0, 2-222 O-ringClear Sorting & Filtering Show Filter Hide Filter
Catalog Number	Nominal Pore Size	Cartridge Nominal Length
CP1501S03	1.0 µm	10 in. (25 cm)
CP1502S03	1.0 µm	20 in. (50 cm)
CP1503S03	1.0 µm	30 in. (75 cm)
CP1504S03	1.0 µm	40 in. (100 cm)
CP2001S03	2.0 µm	10 in. (25 cm)
CP2002S03	2.0 µm	20 in. (50 cm)
CP2003S03	2.0 µm	30 in. (75 cm)
CP2004S03	2.0 µm	40 in. (100 cm)

To order cartridges with other o-ring material than the standard silicone, replace the 7th digit by E for ethylene-propylene or V for fluoroelastomer.
Packaged 3 cartridges per box

AP15 and AP20 · Code 5, 2-222 O-ring w/spearClear Sorting & Filtering Show Filter Hide Filter
Catalog Number	Nominal Pore Size	Cartridge Nominal Length
CP1553S03	1.0 µm	30 in. (75 cm)
CP2051S03	2.0 µm	10 in. (25 cm)

To order cartridges with other o-ring material than the standard silicone, replace the 7th digit by E for ethylene-propylene or V for fluoroelastomer.
Packaged 3 cartridges per box

AP15 and AP20 · Code 7, 2-226 O-ring w/locking-tabs and spearClear Sorting & Filtering Show Filter Hide Filter
Catalog Number	Nominal Pore Size	Cartridge Nominal Length
CP1571S03	1.0 µm	10 in. (25 cm)
CP1572S03	1.0 µm	20 in. (50 cm)
CP1573S03	1.0 µm	30 in. (75 cm)
CP2071S03	2.0 µm	10 in. (25 cm)
CP2072S03	2.0 µm	20 in. (50 cm)
CP2073S03	2.0 µm	30 in. (75 cm)
CP2074S03	2.0 µm	40 in. (100 cm)

To order cartridges with other o-ring material than the standard silicone, replace the 7th digit by E for ethylene-propylene or V for fluoroelastomer.
Packaged 3 cartridges per box

AP15 and AP20 · Code M, 2-118 O-ringClear Sorting & Filtering Show Filter Hide Filter
Catalog Number	Nominal Pore Size	Cartridge Nominal Length
CP15M4S03	1.0 µm	4 in. (10 cm)
CP20M4S03	2.0 µm	4 in. (10 cm)

To order cartridges with other o-ring material than the standard silicone, replace the 7th digit by E for ethylene-propylene or V for fluoroelastomer.
Packaged 3 cartridges per box

AP15 and AP20 · Code N, 2-226 O-ringClear Sorting & Filtering Show Filter Hide Filter
Catalog Number	Nominal Pore Size	Cartridge Nominal Length
CP15N4S03	1.0 µm	4 in. (10 cm)
CP20N4S03	2.0 µm	4 in. (10 cm)

To order cartridges with other o-ring material than the standard silicone, replace the 7th digit by E for ethylene-propylene or V for fluoroelastomer.
Packaged 3 cartridges per box

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Biopharmaceutical Manufacturing > Downstream Processing > Bioburden Reduction/Particulate Control > Membrane based > Lifegard

C517Superior filters for the clarification and prefiltration of viscous biological fluids when high contaminant holding capacity is required

Description

Lifegard™ glass microfiber medium was designed for removal of deformable and non-deformable particles and microorganisms from liquids. Versatile depth-type products retain contaminants within the matrix of glass microfiber medium. The Lifegard™ media is used to achieve exceptional retention efficiency. Because of its high holding capacity, adsorptive removal properties and excellent wet strength, it is very well-suited for the clarification and prefiltration of serum, plasma proteins, gene therapy and other viscous biologicals.

Lifegard™ cartridge filters are ideally suited for processes that require maximum pressure differentials. Cartridges are robust, strong, resilient and are designed to withstand multiple steam-in-place cycles.

Regulatory Compliance

Filters with Lifegard™ media are designed, developed, and manufactured in accordance with a Quality Management System approved by an accredited registering body to an ISO® 9000 Quality Systems Standard and are shipped with a Certificate of Quality for documentation accuracy. Each cartridge filter is supported by a Validation Guide for compliance with regulatory requirements.

For traceability and easy identification, each filter is marked with identifying characteristics.

Multiple Formats Available

A full range of filtration areas is available to suit your application requirements. A variety of connection options are offered for easy adaptation to existing housings.

The Filter of Choice in Plasma Proteins and Serum Applications

Lifegard™ filters protect downstream sterile filters and chromatography columns while effectively removing contaminants and retaining valuable fractions of interest. These filters will remove colloids, aggregated and non-product proteins, lipids and other particles before downstream purification.

	Per 10-inch Cartridge Filter
Materials of Construction
Filter Media	Borosilicate Glass Fiber (BGF)
Supports	Polypropylene
Structural Components	Polypropylene
O-rings	Silicone (SI)
Filtration Area	0.46 m²
Maximum Differential Pressure, bar (psid)	3.5 bar (50 psid) @ 25 °C
Bacterial Endotoxins	Aqueous extraction contains ≤1.0 EU/mL as determined by the Limulus Amebocyte Lysate (LAL) Test
Gravimetric Extractables	The extractables level was equal to or less than 250 mg per 10-inch cartridge after 24 hours in water at controlled room temperature.
Oxidizable Substances	Will meet the USP Oxidizable Substances Test requirements after a water flush of ≥5 L
Component Material Toxicity	Component materials meet the criteria of the USP <88> Reactivity Test for Class VI Plastics. These products meet the requirements of the USP <88> Safety Test, utilizing a 0.9% sodium chloride extraction.
Sterilization	10 autoclave cycles or SIP @ 121 °C for 30 min
Sanitization	30 min with hot water @ 80 °C
Good Manufacturing Practices	These products are manufactured in a facility which adheres to FDA Good Manufacturing Practices.
Indirect Food Additive	All component materials meet the FDA Indirect Food Additive requirements cited in 21 CFR 177-182.

Typical Clean Water Flow Rate vs Pressure Drop

10-inch Cartridge Filters with Lifegard Media — 1.0 and 2.0 µm Nominal

10-inch Cartridge Filters with Lifegard Media — 1.0 and 2.0 µm Nominal

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