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14-928M MST4, active

MST4, active MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
14-928M
250 µg  Also available in 10μg size as catalog # 14-928 and in bulk as catalog # 14-928-K.
Purchase on Sigma-Aldrich

Overview

Replacement Information
Description
Catalogue Number14-928M
Trade Name
  • Upstate
DescriptionMST4, active
OverviewMST4 is a member of the GCK group III family of kinases, which are a subset of the Ste20-like kinases. This protein kinase contains an amino-terminal kinase domain, and a carboxy-terminal regulatory domain that mediates homodimerization. The protein kinase localizes to the Golgi apparatus and is specifically activated by binding to the Golgi matrix protein GM130. It is also cleaved by caspase-3 in vitro, and may function in the apoptotic pathway.
References
Product Information
Presentation50mM Tris/HCl pH7.5, 300mM NaCl, 0.1mM EGTA, 0.03% Brij-35, 270mM sucrose, 1mM benzamidine, 0.2mM PMSF, 0.1% 2-mercaptoethanol
Quality LevelMQ100
Applications
Key Applications
  • Kinase Assay
Biological Information
SourceN-terminal 6His-tagged, recombinant, human MST4 amino acids 4-304 expressed by baculovirus in Sf21 insect cells
Specific ActivityFor Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.
Entrez Gene Number
Gene Symbol
  • MST4
  • MST-4
  • MASK
Purification MethodPurified using Ni2+/NTA agarose.
Target Sub-FamilySTE
UniProt Number
Molecular Weight38 kDa
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceRoutinely evaluated by phosphorylation of peptide RLGRDKYKTLRQIRQ
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage Conditions6 months at -70°C
Packaging Information
Material Size250 µg
Material PackageAlso available in 10μg size as catalog # 14-928 and in bulk as catalog # 14-928-K.
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalog Number GTIN
14-928M 04053252919022

Related Products & Applications

Alternative Packsize

Catalog Number Description
14-928 MST4, active

Product Families

Kinase & Phosphatase Products

Millipore offers a large portfolio of Kinases, Phophatases, Substrates, Inhibitors, Kits, reagents & tools for Signaling research. See below for a list of these products, in multiple pack sizes.
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Categories

Life Science Research > Proteins and Enzymes > Purified Kinases
Life Science Research > Drug Discovery and Development > Kinase & Phosphatase Screening > Purified Kinases