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FCMAB216AP Milli-Mark™ Anti-CD138-APC Antibody, clone MI15

Detect CD138-APC using this Milli-Mark Anti-CD138-APC Antibody, clone MI15 validated for use in FC.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Inflammation & Immunology Research Sub-Category: Immunoglobulins & Immunology UniProt Number: P18827
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FCMAB216AP
100 tests  
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Key Specifications Table

Species ReactivityKey ApplicationsHostFormatAntibody Type
HFCMAPCMonoclonal Antibody
Description
Catalogue NumberFCMAB216AP
Trade Name
  • Milli-Mark
DescriptionMilli-Mark™ Anti-CD138-APC Antibody, clone MI15
Alternate Names
  • Syndecan-1
  • SYND1
Background InformationCD138 is a transmembrane proteoglycan, bearing heparin sulphates and sometimes chondriotin sulfates. It consists of a 30.5 kDa core protein with 5 putative glycosaminoglycans attachment sites. CD138 is a member of the syndecan family. The reported Mr of CD138 ranges from 85,000 to 92,000, presumably depending on the glycosaminoglycan pattern of the molecule (Wijdenes, 1997). Within the hematopoietic system, CD138 is mainly confined to late stages of B-cell differentiation. It is typically expressed at high cellular density in plasma cells (Gattei, 1999). In mature tissues, CD138 is expressed by simple and stratified epithelia, fibroblasts, stratified keratinocytes and endothelial cells (Wijdenes, 1997). Anti-CD138, MI15, was included in the Sixth International Workshop and Conference on Human Leucocytes Differentiation Antigens, and studies by a number of different laboratories confirmed its reactivity with CD138 (Wijdenes, 1997).
References
Product Information
FormatAPC
Control
  • U266 cells
PresentationPurified Mouse monoclonal IgG1 conjugated to APC in 0.05M Tris-HCl buffer with 1% BSA, Sodium Azide at 0.097% at pH 7.2.
Quality LevelMQ100
Applications
ApplicationDetect CD138-APC using this Milli-Mark Anti-CD138-APC Antibody, clone MI15 validated for use in FC.
Key Applications
  • Flow Cytometry
Biological Information
ImmunogenA mixture of U266 and XG-1 human myeloma cell lines
CloneMI15
HostMouse
SpecificityAntibody recognizes Human CD138 antigen.
IsotypeIgG1κ
Species Reactivity
  • Human
Antibody TypeMonoclonal Antibody
Entrez Gene Number
Entrez Gene SummaryThe protein encoded by this gene is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. The syndecan-1 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. Altered syndecan-1 expression has been detected in several different tumor types. While several transcript variants may exist for this gene, the full-length natures of only two have been described to date. These two represent the major variants of this gene and encode the same protein.
Purification MethodProtein A Purfied
UniProt Number
UniProt SummaryCell surface proteoglycan that bears both heparan sulfate and chondroitin sulfate and that links the cytoskeleton to the interstitial matrix.
Molecular Weight 85-92 kDa (Wijdenes, 1997)
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by flow cytometry using U266 cells
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsMaintain refrigerated at 2-8°C protected from light in undiluted aliquots for up to 6 months from date of receipt.
Packaging Information
Material Size100 tests
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalog Number GTIN
FCMAB216AP 04053252480256

Documentation

Milli-Mark™ Anti-CD138-APC Antibody, clone MI15 SDS

Title

Safety Data Sheet (SDS) 

Milli-Mark™ Anti-CD138-APC Antibody, clone MI15 Certificates of Analysis

TitleLot Number
Milli-Mark Anti-CD138-APC, clone MI15 - 1959228 1959228
Milli-Mark Anti-CD138-APC, clone MI15 - 2246799 2246799
Milli-Mark Anti-CD138-APC, clone MI15 - NRG1779492 NRG1779492
Milli-Mark™ Anti-CD138-APC, clone MI15 - 3860232 3860232
Milli-Mark™ Anti-CD138-APC, clone MI15 -2814535 2814535
Milli-Mark™ Anti-CD138-APC, clone MI15- 3783219 3783219
Milli-Mark™ Anti-CD138-APC, clone MI15 - 2430564 2430564