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MPC4NTR10 MultiScreen Permeability Filter Plate, 0.4 µm, non-sterile

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MPC4NTR10
10  
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Overview

Replacement Information
Description
Catalogue NumberMPC4NTR10
Trade Name
  • MultiScreen
DescriptionMultiScreen Permeability Filter Plate, 0.4 µm, non-sterile
Background InformationIncreasing drug candidate predictability earlier in the discovery pipeline using non-cell-based assays can improve candidate throughput during the ADME stage. Non-cell-based permeability assays are predictive models for oral absorption of development candidates.

MultiScreen Permeability, MultiScreen-IP, and MultiScreen Acceptor plates support artificial membrane strategies for predicting passive transport.

Membranes have uniform pore structure and density for reliable transport:
- Individual wells minimize candidate cross-talk
- Compatibility with automated liquid handling systems increases throughput

Permeability Assay:
- The MultiScreen Permeability plate has a polycarbonate membrane, which supports a hexane/hexadecane artificial layer for permeability assays.1

PAMPA Assay:
- The MultiScreen-IP plate has a hydrophobic PVDF membrane, which supports a lipid bilayer for PAMPA asays.2,3

MultiScreen Acceptor Plate:
- The MultiScreen Acceptor plate can be used with either plate to capture passively transported compounds. Constructed of 100% PTFE, the plate can improve LC/MS results depending on the charge of the small molecules being evaluated.
References
Product Information
HS Code8421 29 90
Automation CompatibleNo
Filter CodePCF
Color CodeClear
Number of Wells96
Quality LevelMQ400
Applications
ApplicationThis 96-well filter plate has a Polycarbonate membrane used for Permeability studies.
Key Applications
  • Receptor/Ligand Binding Assays
  • Sample Prep
  • Enzyme Assays with Precipitation
  • DNA Purification
  • PAMPA
Biological Information
SterilityNon-Sterile
Physicochemical Information
Pore Size0.4 µm
Dimensions
Volume100 µL
Materials Information
Chemistry
  • Polycarbonate (PC)
Device Material
  • Styrene
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Packaging Information
Material Size10
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalog Number GTIN
MPC4NTR10 04053252665202