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454575 N-Methyl-D-aspartic Acid, Hydrate - CAS 6384-92-5 - Calbiochem

Excitatory amino acid neurotransmitter.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: NMDA

Primary Target: Glutamate receptor that regulates Ca2+ channels
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Overview

Replacement Information

Key Specifications Table

CAS #Empirical Formula
6384-92-5C₅H₉NO₄•H₂O

Products

Catalog NumberPackaging Qty/Pack
454575-100MG Plastic ampoule 100 mg
Description
OverviewExcitatory amino acid neurotransmitter. Selective agonist of the glutamate receptor that regulates Ca2+ channels. Important in long-term potentiation, ischemia, and epilepsy. NMDA receptors are involved in the "fine tuning" of synaptic connections in the developing brain. Chronic treatment with NMDA produces structural changes in synaptic morphology. Over-excitation of NMDA receptors causes neuronal degeneration and cell death.
Catalogue Number454575
Brand Family Calbiochem®
SynonymsNMDA
References
ReferencesMattson, M.P., et al. 1993. J. Neurosci. 13, 4575.
Yen, L-H., et al. 1993. J. Neurosci. 13, 4949.
Swann, J.W., et al. 1992. Epilepsy Res. Suppl. 9, 115.
Product Information
CAS number6384-92-5
ATP CompetitiveN
FormWhite solid
Hill FormulaC₅H₉NO₄•H₂O
Chemical formulaC₅H₉NO₄•H₂O
ReversibleN
Structure formula ImageStructure formula Image
Quality LevelMQ100
Applications
Biological Information
Primary TargetGlutamate receptor that regulates Ca2+ channels
Purity>95% by TLC
Physicochemical Information
Cell permeableN
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
RTECSCI9457000
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Standard Handling
Storage +15°C to +30°C
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, store in the refrigerator (4°C). Stock solutions are stable for several days at 4°C.
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalog Number GTIN
454575-100MG 04055977204148

Documentation

N-Methyl-D-aspartic Acid, Hydrate - CAS 6384-92-5 - Calbiochem SDS

Title

Safety Data Sheet (SDS) 

N-Methyl-D-aspartic Acid, Hydrate - CAS 6384-92-5 - Calbiochem Certificates of Analysis

TitleLot Number
454575

References

Reference overview
Mattson, M.P., et al. 1993. J. Neurosci. 13, 4575.
Yen, L-H., et al. 1993. J. Neurosci. 13, 4949.
Swann, J.W., et al. 1992. Epilepsy Res. Suppl. 9, 115.

Brochure

Title
Excitotoxic Glutamate Analogs Technical Bulletin
Pathways and Biomarkers of Glutamatergic Synapse Flyer
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision30-August-2007 JSW
SynonymsNMDA
DescriptionAn excitatory amino acid neurotransmitter. Selective agonist of the glutamate receptor that regulates Ca2+ channels. Important in long-term potentiation, ischemia, and epilepsy. NMDA receptors are involved in the "fine tuning" of synaptic connections in the developing brain. Chronic treatment with NMDA produces structural changes in synaptic morphology. Over-excitation of NMDA receptors causes neuronal degeneration and cell death.
FormWhite solid
CAS number6384-92-5
RTECSCI9457000
Chemical formulaC₅H₉NO₄•H₂O
Structure formulaStructure formula
Purity>95% by TLC
SolubilityH₂O (1 mg/ml)
Storage +15°C to +30°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, store in the refrigerator (4°C). Stock solutions are stable for several days at 4°C.
Toxicity Standard Handling
Merck USA index14, 6662
ReferencesMattson, M.P., et al. 1993. J. Neurosci. 13, 4575.
Yen, L-H., et al. 1993. J. Neurosci. 13, 4949.
Swann, J.W., et al. 1992. Epilepsy Res. Suppl. 9, 115.