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480001 NDSB-195 - CAS 160255-06-1 - Calbiochem

A non-detergent sulfobetaine. Reported to prevent protein aggregation and facilitate the renaturation of chemically and thermally denatured proteins.

NDSB-195 - CAS 160255-06-1 - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: Dimethylethylammonium Propane Sulfonate

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Overview

Replacement Information

Key Specifications Table

CAS #Empirical Formula
160255-06-1C₇H₁₇NO₃S

Products

Catalog NumberPackaging Qty/Pack
480001-25GM Glass bottle 25 gm
480001-5GM Plastic ampoule 5 gm
Description
OverviewA non-detergent sulfobetaine. Reported to prevent protein aggregation and facilitate the renaturation of chemically and thermally denatured proteins. Zwitterionic over a wide pH range. Does not absorb significantly in the near-UV range. Easily removed by dialysis.
Catalogue Number480001
Brand Family Calbiochem®
SynonymsDimethylethylammonium Propane Sulfonate
References
ReferencesGoldberg, M.E., et al. 1996. Folding & Design 1, 21.
Vuillard, L., et al. 1995. Anal. Biochem. 230, 290.
Vuillard, L., et al. 1995. Biochem. J. 305, 337.
Vuillard, L., et al. 1994. FEBS Lett. 353, 294.
Product Information
CAS number160255-06-1
FormWhite solid
Hill FormulaC₇H₁₇NO₃S
Chemical formulaC₇H₁₇NO₃S
Hygroscopic Hygroscopic
Structure formula ImageStructure formula Image
Quality LevelMQ100
Applications
Biological Information
Purity≥95% by TLC
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
R PhraseR: 36/37/38

Irritating to eyes, respiratory system and skin.
S PhraseS: 26-36

In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
Wear suitable protective clothing.
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Irritant
Storage +15°C to +30°C
Hygroscopic Hygroscopic
Do not freeze Ok to freeze
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalog Number GTIN
480001-25GM 04055977201758
480001-5GM 04055977201765

Documentation

NDSB-195 - CAS 160255-06-1 - Calbiochem SDS

Title

Safety Data Sheet (SDS) 

NDSB-195 - CAS 160255-06-1 - Calbiochem Certificates of Analysis

TitleLot Number
480001

References

Reference overview
Goldberg, M.E., et al. 1996. Folding & Design 1, 21.
Vuillard, L., et al. 1995. Anal. Biochem. 230, 290.
Vuillard, L., et al. 1995. Biochem. J. 305, 337.
Vuillard, L., et al. 1994. FEBS Lett. 353, 294.

Brochure

Title
Detergents Booklet
Protein Purification and Detection Tools
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision13-April-2011 RFH
SynonymsDimethylethylammonium Propane Sulfonate
DescriptionA member of the class of nondetergent sulfobetaines. Unlike CHAPS and other zwittergents, NDSBs are nondenaturing even at 1 M concentrations. NDSBs have been used to improve the efficiency of solubilization of membrane proteins, to isolate nuclear proteins, to chromatographically purify halophilic proteins in low ionic strength buffers, and to crystallize proteins. They are zwitterionic over a wide pH range and do not absorb significantly in the near UV range. Reported to prevent protein aggregation and facilitate the renaturation of chemically and thermally denatured proteins. NDSBs can be easily removed by dialysis.
FormWhite solid
CAS number160255-06-1
Chemical formulaC₇H₁₇NO₃S
Structure formulaStructure formula
Purity≥95% by TLC
SolubilityH₂O
Storage +15°C to +30°C
Hygroscopic
Do Not Freeze Ok to freeze
Toxicity Irritant
ReferencesGoldberg, M.E., et al. 1996. Folding & Design 1, 21.
Vuillard, L., et al. 1995. Anal. Biochem. 230, 290.
Vuillard, L., et al. 1995. Biochem. J. 305, 337.
Vuillard, L., et al. 1994. FEBS Lett. 353, 294.