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480005 NDSB-201 - CAS 15471-17-7 - Calbiochem

A non-detergent sulfobetaine. Reported to prevent protein aggregation and facilitate the renaturation of chemically and thermally denatured proteins. Zwitterionic over a wide pH range. Easily removed by dialysis.

NDSB-201 - CAS 15471-17-7 - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: 3-(1-Pyridino)-1-propane Sulfonate

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Overview

Replacement Information

Key Specifications Table

CAS #Empirical Formula
15471-17-7C₈H₁₁NO₃S

Products

Catalog NumberPackaging Qty/Pack
480005-250GM Glass bottle 250 gm
480005-25GM Plastic ampoule 25 gm
Description
OverviewA non-detergent sulfobetaine. Reported to prevent protein aggregation and facilitate the renaturation of chemically and thermally denatured proteins. Zwitterionic over a wide pH range. Easily removed by dialysis.
Catalogue Number480005
Brand Family Calbiochem®
Synonyms3-(1-Pyridino)-1-propane Sulfonate
References
ReferencesGoldberg, M.E., et al. 1996. Folding & Design 1, 21.
Vuillard, L., et al. 1995. Biochem. J. 305, 337.
Product Information
CAS number15471-17-7
FormWhite powder
Hill FormulaC₈H₁₁NO₃S
Chemical formulaC₈H₁₁NO₃S
Hygroscopic Hygroscopic
Structure formula ImageStructure formula Image
Quality LevelMQ100
Applications
Biological Information
Purity≥99% by titration
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
R PhraseR: 36/37/38

Irritating to eyes, respiratory system and skin.
S PhraseS: 26-36

In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
Wear suitable protective clothing.
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Irritant
Storage +15°C to +30°C
Hygroscopic Hygroscopic
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, store at room temperature. Stock solutions are stable for up to 3 months at room temperature.
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalog Number GTIN
480005-250GM 04055977201789
480005-25GM 04055977201772

Documentation

NDSB-201 - CAS 15471-17-7 - Calbiochem SDS

Title

Safety Data Sheet (SDS) 

NDSB-201 - CAS 15471-17-7 - Calbiochem Certificates of Analysis

TitleLot Number
480005

References

Reference overview
Goldberg, M.E., et al. 1996. Folding & Design 1, 21.
Vuillard, L., et al. 1995. Biochem. J. 305, 337.

Certificates

Title

Brochure

Title
Detergents Booklet
Protein Purification and Detection Tools

Citations

Title
  • Leslie Lobel, et al. (2002) Bacterial expression of a natively folded extracellular domain fusion protein of the hFSH receptor in the cytoplasm of Escherichia coli. Protein Expression and Purification 25, 124-133.
    		•
    Data Sheet

    Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

    Revision28-February-2008 JSW
    Synonyms3-(1-Pyridino)-1-propane Sulfonate
    DescriptionA member of the class of nondetergent sulfobetaines. Unlike CHAPS and other zwittergents, NDSBs are nondenaturing even at 1 M concentrations. NDSBs have been used to improve the efficiency of solubilization of membrane proteins, to isolate nuclear proteins, to chromatographically purify halophilic proteins in low ionic strength buffers, and to crystallize proteins. They are zwitterionic over a wide pH range and do not absorb significantly in the near UV range. Reported to prevent protein aggregation and facilitate the renaturation of chemically and thermally denatured proteins. NDSBs can be easily removed by dialysis.
    FormWhite powder
    CAS number15471-17-7
    Chemical formulaC₈H₁₁NO₃S
    Structure formulaStructure formula
    Purity≥99% by titration
    SolubilityH₂O (50 mg/ml)
    Storage +15°C to +30°C
    Hygroscopic
    Do Not Freeze Ok to freeze
    Special InstructionsFollowing reconstitution, store at room temperature. Stock solutions are stable for up to 3 months at room temperature.
    Toxicity Irritant
    ReferencesGoldberg, M.E., et al. 1996. Folding & Design 1, 21.
    Vuillard, L., et al. 1995. Biochem. J. 305, 337.
    Citation
  • Leslie Lobel, et al. (2002) Bacterial expression of a natively folded extracellular domain fusion protein of the hFSH receptor in the cytoplasm of Escherichia coli. Protein Expression and Purification 25, 124-133.
    		•