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165350 PARP Inhibitor I, 3-ABA - CAS 3544-24-9 - Calbiochem

The PARP Inhibitor I, 3-ABA, also referenced under CAS 3544-24-9, controls the biological activity of PARP. This small molecule/inhibitor is primarily used for Cell Structure applications.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: 3-Aminobenzamide

Primary Target: PARP
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Overview

Replacement Information

Key Specifications Table

CAS #Empirical Formula
3544-24-9C₇H₈N₂O

Products

Catalog NumberPackaging Qty/Pack
165350-100MG Plastic ampoule 100 mg
Description
OverviewA cell-permeable anti-proliferative agent that acts as an inhibitor of poly(ADP-ribose) polymerase (PARP). Has minimal effect on bacterial toxin-mediated ADP-ribosylation. An inhibitor of UV-induced apoptosis. Also strongly inhibits K562 target cell killing by human effector natural killer cells.
Catalogue Number165350
Brand Family Calbiochem®
Synonyms3-Aminobenzamide
References
ReferencesTiozzo, R., et al. 1996. Biochem. Biophys. Res. Commun. 225, 826.
Malorni, W., et al. 1995. Biochem. Biophys. Res. Commun. 207, 715.
Malorni, W., et al. 1994. Biochem. Biophys. Res. Commun. 199, 1250.
Monti, D., et al. 1994. Biochem. Biophys. Res. Commun. 199, 525.
Kozak, K.R., and Ross, I.A. 1991. Biochem. Biophys. Res. Commun. 179, 1225.
Product Information
CAS number3544-24-9
ATP CompetitiveN
FormWhite solid
Hill FormulaC₇H₈N₂O
Chemical formulaC₇H₈N₂O
ReversibleN
Structure formula ImageStructure formula Image
Quality LevelMQ100
Applications
Biological Information
Primary TargetPARP
Purity≥99% by GC
Physicochemical Information
Cell permeableY
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
RTECSCU8992000
Safety Information
R PhraseR: 36/37/38

Irritating to eyes, respiratory system and skin.
S PhraseS: 26-36

In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
Wear suitable protective clothing.
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Irritant
Storage +15°C to +30°C
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C ). Stock solutions are stable for 3 months at -20°C.
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalog Number GTIN
165350-100MG 04055977207675

Documentation

PARP Inhibitor I, 3-ABA - CAS 3544-24-9 - Calbiochem SDS

Title

Safety Data Sheet (SDS) 

PARP Inhibitor I, 3-ABA - CAS 3544-24-9 - Calbiochem Certificates of Analysis

TitleLot Number
165350

References

Reference overview
Tiozzo, R., et al. 1996. Biochem. Biophys. Res. Commun. 225, 826.
Malorni, W., et al. 1995. Biochem. Biophys. Res. Commun. 207, 715.
Malorni, W., et al. 1994. Biochem. Biophys. Res. Commun. 199, 1250.
Monti, D., et al. 1994. Biochem. Biophys. Res. Commun. 199, 525.
Kozak, K.R., and Ross, I.A. 1991. Biochem. Biophys. Res. Commun. 179, 1225.
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision01-May-2014 JSW
Synonyms3-Aminobenzamide
DescriptionA cell-permeable anti-proliferative agent that acts as an inhibitor of poly(ADP-ribose) polymerase (PARP). Has minimal effect on bacterial toxin-mediated ADP-ribosylation. An inhibitor of UV-induced apoptosis. Also strongly inhibits K562 target cell killing by human effector natural killer cells.
FormWhite solid
CAS number3544-24-9
RTECSCU8992000
Chemical formulaC₇H₈N₂O
Structure formulaStructure formula
Purity≥99% by GC
SolubilityDMSO (5 mg/ml), Ethanol (1 mg/ml), or H₂O (1 mg/ml)
Storage +15°C to +30°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C ). Stock solutions are stable for 3 months at -20°C.
Toxicity Irritant
ReferencesTiozzo, R., et al. 1996. Biochem. Biophys. Res. Commun. 225, 826.
Malorni, W., et al. 1995. Biochem. Biophys. Res. Commun. 207, 715.
Malorni, W., et al. 1994. Biochem. Biophys. Res. Commun. 199, 1250.
Monti, D., et al. 1994. Biochem. Biophys. Res. Commun. 199, 525.
Kozak, K.R., and Ross, I.A. 1991. Biochem. Biophys. Res. Commun. 179, 1225.