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106887 Papanicolaou’s solution 2b Orange II solution

for cytology

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106887
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Overview

Replacement Information

Products

Catalog NumberPackaging Qty/Pack
1068870500 Plastic bottle 500 ml
1068872500 Plastic bottle 2.5 l
Description
Catalogue Number106887
DescriptionPapanicolaou's solution 2b Orange II solution
OverviewPapanicolaou’s solution 2b Orange II solution - for cytology, is a ready-to-use solution used for human-medical cell diagnosis and serve the purpose of the cytological investigation of sample material of human origin, for example, cervical smears. Papanicolaou’s technique is the most used staining procedure for cytological specimens and is intended for the the staining of exfoliative cells in cytological specimens.
In the first step, the cell nuclei are stained either progressively or regressively with a hematoxylin solution, (Hematoxylin solution modified acc.to Gill II, (Cat.no. 105175),
Papanicolaou’s solution 1a Harris hematoxylin solution, (Cat.no. 109253) or Papanicolaou’s solution 1b Hematoxylin solution S, (Cat.no. 109254)). Nuclei are stained blue to dark violet. In the progressive hematoxylin staining method, staining is carried out to the endpoint, after which the slide is blued in tapwater. With the regressive method the material is over-stained and the excess of staining solution is removed by acid rinsing steps, followed by the bluing step. The structures of nuclei are more differentiated and better visible by the regressive method. The second staining step is cytoplasmic staining by orange staining solution, (Papanicolaou’s solution 2b Orange II solution, (Cat. no. 1106887) or Papanicolaou’s solution 2a Orange G solution (OG6), (Cat. no. 106888)), especially for demonstration of mature and keratinized cells. The target structures are stained orange in different intensities. In the third staining step is used the so-called polychrome solution, a mixture of eosin, light green SF and Bismarck brown, Papanicolaou’s solution 3a polychromatic solution EA 31, (Cat.no 109271), Papanicolaou’s solution 3b polychromatic solution EA 50, (Cat.no. 109272), Papanicolaou’s solution 3c polychromatic solution EA 65,(Cat.no. 109270), or Papanicolaou’s solution 3d polychromatic solution EA 65, (Cat.no.109269). The polychrome solution is used for demonstration of differentiation of squamous cells. Papanicolaou’s solution 2b Orange II solution gives a more intense reddish staining result with mature and keratinized squamous cells than Papanicolaou’s solution 2a Orange G solution (OG6) - for cytology.
The 500 ml bottle provides 1500 - 2000 stainings. For more details, please see instructions for use (IFU). This product is registered as IVD and CE marked.
References
Product Information
HS Code3204 12 10
Quality LevelMQ400
Applications
Applicationfor cytology
Biological Information
Physicochemical Information
Density0.83 g/cm3 (20 °C)
Flash point17 °C
pH value7.0 - 7.5 (H₂O, 20 °C)
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Hazard Pictogram(s) Hazard Pictogram(s)
Hazard Pictogram(s)
Hazard Pictogram(s)
Hazard Statement(s)H225: Highly flammable liquid and vapour.
H302 + H312 + H332: Harmful if swallowed, in contact with skin or if inhaled.
H319: Causes serious eye irritation.
H370: Causes damage to organs.
Precautionary Statement(s)P210: Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
P280: Wear protective gloves/ protective clothing/ eye protection/ face protection/ hearing protection.
P301 + P312: IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell.
P303 + P361 + P353: IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water.
P304 + P340 + P312: IF INHALED: Remove person to fresh air and keep comfortable for breathing. Call a POISON CENTER/doctor if you feel unwell.
P308 + P311: IF exposed or concerned: Call a POISON CENTER/doctor.
P403 + P233: Store in a well-ventilated place. Keep container tightly closed.
Signal WordDanger
Storage class3 Flammable liquids
WGKWGK 2 obviously hazardous to water
Disposal1
Strongly contaminated halogen-free organic solvents: container A.
Safety Information
Categories of dangerhighly flammable, toxic
Product Usage Statements
Storage and Shipping Information
StorageStore at +15°C to +25°C.
Packaging Information
Transport Information
Declaration (railroad and road) ADR, RIDUN 1987 , 3, II
Declaration (transport by air) IATA-DGRUN 1987 , 3, II
Declaration (transport by sea) IMDG-CodeUN 1987 , 3, II
Supplemental Information
Specifications
Suitability for microscopy (Vaginal smear)passes test
Nucleiblue to dark violet
Cyanophilic Cytoplasm (basophilic)blue-green
Eosinophilic Cytoplasm (acidophilic)pink
Global Trade Item Number
Catalog Number GTIN
1068870500 04022536084084
1068872500 04022536084107

Related Products & Applications

Accessories (Primary)

Catalog Number Description
106888 Papanicolaou's solution 2a Orange G solution (OG 6)
109254 Papanicolaou's solution 1b Hematoxylin solution S
109269 Papanicolaou's solution 3d polychromatic solution EA 65
109271 Papanicolaou's solution 3a polychromatic solution EA 31
109270 Papanicolaou's solution 3c Polychromatic solution EA 65

Accessories (Secondary)

Catalog Number Description
106888 Papanicolaou's solution 2a Orange G solution (OG 6)
109254 Papanicolaou's solution 1b Hematoxylin solution S
109269 Papanicolaou's solution 3d polychromatic solution EA 65
109271 Papanicolaou's solution 3a polychromatic solution EA 31
109270 Papanicolaou's solution 3c Polychromatic solution EA 65

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Clinical Cytology
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Papanicolaou

Categories

IVD/OEM Materials & Reagents > Microscopy > Cytology > Cytological Staining Reagents