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506125 Paroxetine Hydrochloride - CAS 110429-35-1 - Calbiochem

Paroxetine Hydrochloride is a very potent uptake inhibitor highly selective for 5-HT transporter.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: 5-HT transporter, Paroxetine, Paxil

Primary Target: 5-HT Uptake Transporter
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Overview

Replacement Information

Key Specifications Table

CAS #Empirical Formula
110429-35-1C₁₉H₂₀FNO₃·HCl

Products

Catalog NumberPackaging Qty/Pack
5.06125.0001 Glass bottle 10 mg
Description
OverviewA very potent uptake inhibitor highly selective for 5-HT transporter (Ki = 0.065 nM and 0.05 nM for human and rat 5-HT transporters, respectively). A popular antidepressant drug of the SSRI type. Used to treat major depression, obsessive-compulsive disorder, panic disorder, social anxiety, posttraumatic stress disorder, generalized anxiety disorder and vasomotor symptoms.
Catalogue Number506125
Brand Family Calbiochem®
Synonyms5-HT transporter, Paroxetine, Paxil
References
ReferencesBrittain, G., et al. 2012. Profiles of drug substances, excipients, and related methodology. 38, 407.
Bourin, M., et al. 2001. CNS Drug Rev. 7, 25.
Thomas, R., et al. 1997. Psychopharmacology (Berl). 93, 193.
Product Information
CAS number110429-35-1
FormWhite solid
Hill FormulaC₁₉H₂₀FNO₃·HCl
Chemical formulaC₁₉H₂₀FNO₃·HCl
Structure formula ImageStructure formula Image
Quality LevelMQ100
Applications
Biological Information
Primary Target5-HT Uptake Transporter
Primary Target K<sub>i</sub>0.065 nM
Purity≥99% by HPLC
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
Toxicity Standard Handling
Storage +2°C to +8°C
Protect from Light Protect from light
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalog Number GTIN
5.06125.0001 04055977243109

Documentation

Paroxetine Hydrochloride - CAS 110429-35-1 - Calbiochem SDS

Title

Safety Data Sheet (SDS) 

References

Reference overview
Brittain, G., et al. 2012. Profiles of drug substances, excipients, and related methodology. 38, 407.
Bourin, M., et al. 2001. CNS Drug Rev. 7, 25.
Thomas, R., et al. 1997. Psychopharmacology (Berl). 93, 193.
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision17-December-2018 JSW
Synonyms5-HT transporter, Paroxetine, Paxil
DescriptionA very potent uptake inhibitor highly selective for 5-HT transporter (Ki = 0.065 nM and 0.05 nM for human and rat 5-HT transporters, respectively). A popular antidepressant drug of the SSRI type. Used to treat major depression, obsessive-compulsive disorder, panic disorder, social anxiety, posttraumatic stress disorder, generalized anxiety disorder and vasomotor symptoms.
FormWhite solid
CAS number110429-35-1
Chemical formulaC₁₉H₂₀FNO₃·HCl
Structure formulaStructure formula
Purity≥99% by HPLC
SolubilityDMSO
Storage Protect from light
+2°C to +8°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Toxicity Standard Handling
ReferencesBrittain, G., et al. 2012. Profiles of drug substances, excipients, and related methodology. 38, 407.
Bourin, M., et al. 2001. CNS Drug Rev. 7, 25.
Thomas, R., et al. 1997. Psychopharmacology (Berl). 93, 193.