52332 Sigma-AldrichPhenylmethylsulfonyl Fluoride - CAS 329-98-6 - Calbiochem
Phenylmethylsulfonyl Fluoride, CAS 329-98-6, is an irreversible inhibitor of serine proteases. It causes sulfonylation of the active-site serine residues.
More>> Phenylmethylsulfonyl Fluoride, CAS 329-98-6, is an irreversible inhibitor of serine proteases. It causes sulfonylation of the active-site serine residues. Less<<MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Synonyms: Benzylsulfonyl Fluoride, PMSF
Recommended Products
Overview
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Key Specifications Table
| CAS # | Empirical Formula |
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| 329-98-6 | C₇H₇FO₂S |
Products
| Catalog Number | Packaging | Qty/Pack | |
|---|---|---|---|
| 52332-1GM | Alu drum | 1 gm | |
| 52332-25GM | Fibre case | 25 gm | |
| 52332-5GM | Glass bottle | 5 gm |
| Description | |
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| Overview | Irreversible inhibitor of serine proteases. Its mechanism of action is analogous to that of diisopropylfluorophosphate. PMSF causes sulfonylation of the active-site serine residues. Also reported to inhibit internucleosomal DNA fragmentation in immature thymocytes. For a related, more stable inhibitor, see AEBSF (Cat. No. 101500). |
| Catalogue Number | 52332 |
| Brand Family | Calbiochem® |
| Synonyms | Benzylsulfonyl Fluoride, PMSF |
| Product Information | |
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| CAS number | 329-98-6 |
| ATP Competitive | N |
| Form | White to off-white crystalline solid |
| Hill Formula | C₇H₇FO₂S |
| Chemical formula | C₇H₇FO₂S |
| Reconstitution | t½ = 1 hour at pH 7.5. Effective concentration: 50 μM. |
| Reversible | N |
| Structure formula Image | |
| Quality Level | MQ200 |
| Applications |
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| Biological Information | |
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| Primary Target | serine proteases |
| Purity | ≥99% by GC |
| Physicochemical Information | |
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| Cell permeable | N |
| Dimensions |
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| Materials Information |
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| Toxicological Information |
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| Safety Information according to GHS | |
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| RTECS | XT8040000 |
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| Packaging Information |
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| Transport Information |
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| Specifications |
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| Global Trade Item Number | |
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| Catalog Number | GTIN |
| 52332-1GM | 07790788051044 |
| 52332-25GM | 04055977271508 |
| 52332-5GM | 04055977271515 |
Documentation
Phenylmethylsulfonyl Fluoride - CAS 329-98-6 - Calbiochem SDS
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Phenylmethylsulfonyl Fluoride - CAS 329-98-6 - Calbiochem Certificates of Analysis
| Title | Lot Number |
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| 52332 |
References
| Reference overview |
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| Seitz, R., et al. 1993. Int. J. Cancer 53, 514. Weaver, V.M., et al. 1993. Biochem. Cell. Biol. 71, 488. Bourgain, R.H., et al. 1992. Adv. Exp. Med. Biol. 316, 427. Chang, C.T., et al. 1992. Biochem. Int. 28, 707. |
Citations
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Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.
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