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14-738M Pim-3 Protein, active, 250 µg

Active, N-terminal 6His-tagged, recombinant, human Pim-3, for use in Enzyme Assays.

Pim-3 Protein, active, 250 µg MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
14-738M
250 µg  Also available in 10 μg size (cat#14-738) and in bulk (cat# 14-738-K).
Purchase on Sigma-Aldrich

Overview

Replacement Information
Description
Catalogue Number14-738M
Brand Family Upstate
Trade Name
  • Upstate
DescriptionPim-3 Protein, active, 250 µg
OverviewN-terminal 6His-tagged, recombinant, human Pim-3
References
Product Information
Quality LevelMQ100
Applications
ApplicationActive, N-terminal 6His-tagged, recombinant, human Pim-3, for use in Enzyme Assays.
Key Applications
  • Enzyme Assays
Biological Information
Sourceexpressed by baculovirus in Sf21 cells
Specific ActivityFor Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.
Entrez Gene Number
Entrez Gene SummaryPIM3 belongs to a family of protooncogenes that encode serine/threonine protein kinases (Mikkers et al., 2004 [PubMed 15199164]).[supplied by OMIM]
Gene Symbol
  • PIM3
  • pim-3
Protein TargetPim-3
Purification MethodNi2+/NTA-agarose
Target Sub-FamilyCAMK
UniProt Number
UniProt SummaryFUNCTION: SwissProt: Q86V86 # May be involved in cell cycle progression and anti- apoptosis process. Implicated in proliferation of human hepatoma cell lines.
SIZE: 326 amino acids; 35863 Da
TISSUE SPECIFICITY: Widely expressed. No expression in colon, thymus, and small intestine. Expressed in human hepatoma cell lines but not in normal liver tissues.
SIMILARITY: SwissProt: Q86V86 ## Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PIM subfamily. & Contains 1 protein kinase domain.
Molecular Weight39.6kDa
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality Assuranceroutinely evaluated by phosphorylation of 250μM GGMEDIYFEFMGGKKK
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage Conditions6 months at -70°C from date of shipment
Packaging Information
Material Size250 µg
Material PackageAlso available in 10 μg size (cat#14-738) and in bulk (cat# 14-738-K).
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalog Number GTIN
14-738M 04053252367311

Related Products & Applications

Alternative Packsize

Catalog Number Description
14-738 Pim-3 Protein, active, 10 µg

Product Families

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Categories

Life Science Research > Proteins and Enzymes > Purified Kinases
Life Science Research > Drug Discovery and Development > Kinase & Phosphatase Screening > Purified Kinases