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528208 Plasminogen Activator Inhibitor-1, Mutant, Human, Recombinant - Calbiochem

The Plasminogen Activator Inhibitor-1, Mutant, Human, Recombinant controls the biological activity of Plasminogen Activator. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: PAI-1, Mutant

Primary Target: Plasminogen Activator
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Overview

Replacement Information

Products

Catalog NumberPackaging Qty/Pack
528208-50UG Plastic ampoule 50 μg
Description
OverviewHighly purified preparation of an altered form of human PAI-1 containing four mutated amino acids. Mutant PAI-1 is virtually unable to go latent and is stable at elevated temperature and pH for extended periods of time (t½ = 145 hours at 37°C, pH 7.4). Inhibits uPA (Ki = 5.1 x 106 M-1 sec-1) and tPA (Ki = 7.9 x 105 M-1 sec-1).
Catalogue Number528208
Brand Family Calbiochem®
SynonymsPAI-1, Mutant
References
ReferencesBerkenpas, M.B., et al. 1995. EMBO J. 14, 2969.
Product Information
ATP CompetitiveN
FormLiquid
FormulationIn 100 mM NaCl, 50 mM sodium phosphate buffer, 1 mM EDTA, pH 6.6.
ReversibleN
Quality LevelMQ100
Applications
Biological Information
Primary TargetPlasminogen Activator
Primary Target K<sub>i</sub>5.1 x 106 M-1 sec-1, 7.9 x 105 M-1 sec-1 against uPA and tPA, respectively
Purity≥95% by SDS-PAGE assay
Concentration Label Please refer to vial label for lot-specific concentration
Physicochemical Information
Cell permeableN
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Dry Ice Only
Toxicity Standard Handling
Storage ≤ -70°C
Avoid freeze/thaw Avoid freeze/thaw
Do not freeze Ok to freeze
Special InstructionsFollowing initial thaw, aliquot and freeze (-70°C).
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalog Number GTIN
528208-50UG 04055977196498

Documentation

Plasminogen Activator Inhibitor-1, Mutant, Human, Recombinant - Calbiochem SDS

Title

Safety Data Sheet (SDS) 

Plasminogen Activator Inhibitor-1, Mutant, Human, Recombinant - Calbiochem Certificates of Analysis

TitleLot Number
528208

References

Reference overview
Berkenpas, M.B., et al. 1995. EMBO J. 14, 2969.
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision22-July-2024 JSW
SynonymsPAI-1, Mutant
DescriptionHighly purified preparation of an altered form of human PAI-1 containing four mutated amino acids. Mutant PAI-1 is virtually unable to go latent and is stable at elevated temperature and pH for extended periods of time (t½ = 145 h at 37°C, pH 7.4). Inhibits uPA (Ki = 5.1 x 106 M-1sec-1) and tPA (Ki = 7.9 x 105 M-1sec-1).
FormLiquid
FormulationIn 100 mM NaCl, 50 mM sodium phosphate buffer, 1 mM EDTA, pH 6.6.
Concentration Label Please refer to vial label for lot-specific concentration
Purity≥95% by SDS-PAGE assay
Storage Avoid freeze/thaw
≤ -70°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing initial thaw, aliquot and freeze (-70°C).
Toxicity Standard Handling
ReferencesBerkenpas, M.B., et al. 1995. EMBO J. 14, 2969.