ProSep^®-vA High Capacity Chromatography Media

The ProSep^®-vA family of protein A affinity media is designed to facilitate highly efficient, cost effective purification of monoclonal, polyclonal and engineered antibodies. These resins are manufactured using no mammalian derived products.

ProSep^®-vA High Capacity consists of protein A immobilized on porous glass that is permeated by interconnecting pores of uniform and precisely controlled size. ProSep®-vA chromatography media exhibit chemical and mechanical stability over a range of conditions such as low pH, exposure to detergents, buffers of varying ionic strengths and many organic solvents.

Its matrix is optimized for large-scale production use and offers significant advantages compared with other available matrices:

• Proven technology
  
• Rigid and incompressible
  
• High flow rates with low back pressure
  
• No shrinkage or swelling
  
• High throughput and productivity
  
• Reliable scale up
  
• Flexible operating conditions
  
• Lower cost of operation

ProSep^®--vA High Capacity Media

ProSep^®-vA High Capacity media is suited as capture step in the purification of therapeutic antibodies. It was the first commercially available animal free protein A resin, designed for the large-scale purification of monoclonal, polyclonal and engineered antibodies.