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GF311 RANTES Protein, Human Recombinant Animal Free

The RANTES protein, also known as CCL5 protein, is an 8 kDa chemokine that plays a primary role in the inflammatory immune response by means of its ability to attract & activate leukocytes. Manufactured using all non-animal reagents.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
UniProt Number: P13501 Entrez Gene Number: NM_002985.2
GF311
20 µg  
Purchase on Sigma-Aldrich

Overview

Replacement Information

Key Specifications Table

SourcePurity
E. coli Product is endotoxin free (< 0.1ng/μg of protein (<1EU/μg) and greater than 98% pure by SDS-PAGE gel and HPLC analyses
Description
Catalogue NumberGF311
DescriptionRANTES Protein, Human Recombinant Animal Free
Alternate Names
  • CCL5
  • EoCP
  • Eosinophil chemotactic cytokine
  • SIS-delta
  • Small-inducible cytokine A5
  • T cell-specific protein P228
Background InformationRANTES , also known as CCL5, is an 8 kDa chemokine that plays a primary role in the inflammatory immune response by means of its ability to attract and activate leukocytes. RANTES is a CC-chemokine that can signal through the CCR1, CCR3, CCR5 and US28 (cytomegalovirus receptor) receptors. It is a chemoattractant towards monocytes, memory T cells (CD4+/CD45RO), basophils, and eosinophils. RANTES also has the capability to inhibit certain strains of HIV-1, HIV-2 and simian immunodeficiency virus (SIV). Recombinant human RANTES is a 7.8 kDa protein containing 68 amino acid residues including the four highly conserved cysteine residues present in the CC chemokines.
References
Product Information
Formulation
PresentationProduct is filtered through a 0.2 micron filter before lyophilization.
Quality LevelMQ300
Applications
ApplicationThe RANTES protein, also known as CCL5 protein, is an 8 kDa chemokine that plays a primary role in the inflammatory immune response by means of its ability to attract & activate leukocytes. Manufactured using all non-animal reagents.
Biological Information
PurityProduct is endotoxin free (< 0.1ng/μg of protein (<1EU/μg) and greater than 98% pure by SDS-PAGE gel and HPLC analyses
SourceE. coli
Cross ReactivityNone
Entrez Gene Number
UniProt Number
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceBioactivity assay: Determined by its ability to chemoattract human blood monocytes using a concentration range of 1.0-10.0 ng/ml.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStore at -20°C for up to 6 months from date of receipt.
Packaging Information
Material Size20 µg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalog Number GTIN
GF311 04053252691478

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Life Science Research > Cell Culture and Systems > Cell Culture Media and Supplements > Cell Culture Supplements > Cytokines & Growth Factors