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14-647 SGK3 Protein, active, 10 µg

14-647
10 µg  
Purchase on Sigma-Aldrich

Overview

Replacement Information
Description
Catalogue Number14-647
Brand Family Upstate
Trade Name
  • Upstate
DescriptionSGK3 Protein, active, 10 µg
OverviewN-terminal 6His-tagged, recombinant, human SGK3 amino acids 119-end
References
Product Information
Quality LevelMQ100
Applications
ApplicationActive, N-terminal 6His-tagged, recombinant, human SGK3 amino acids 119-end, for use in Kinase Assays.
Key Applications
  • Kinase Assay
Biological Information
SourceExpressed by baculovirus in Sf21 cells
Specific ActivityFor Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme
Entrez Gene Number
Entrez Gene SummaryThis gene is a member of the Ser/Thr protein kinase family and encodes a phosphoprotein with a PX (phox homology) domain. The protein phosphorylates several target proteins and has a role in neutral amino acid transport and activation of potassium and chloride channels. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Gene Symbol
  • SGK3
  • SGK2
  • CISK
  • DKFZp781N0293
  • SGKL
Protein TargetSGK3
Purification MethodNi2+/NTA-agarose
Target Sub-FamilyAGC
UniProt Number
UniProt SummaryFUNCTION: SwissProt: Q96BR1 # Involved in the activation of potassium channels. Mediates cell IL-3-dependent survival signals (By similarity).
SIZE: 496 amino acids; 57108 Da
SUBCELLULAR LOCATION: Cytoplasmic vesicle (By similarity). Early endosome (By similarity). Note=Localized in vesicle-like structures and in the early endosome (By similarity).
TISSUE SPECIFICITY: Expressed in most tissues with highest levels in pancreas, kidney liver, heart and brain and lower levels in lung, placenta and skeletal muscle.
SIMILARITY: SwissProt: Q96BR1 ## Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. & Contains 1 AGC-kinase C-terminal domain. & Contains 1 protein kinase domain. & Contains 1 PX (phox homology) domain.
Molecular Weight46.7kDa
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceRoutinely evaluated by phosphorylation of crosstide KK (12-555)
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage Conditions6 months at -70°C
Packaging Information
Material Size10 µg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalog Number GTIN
14-647 04053252509742

Related Products & Applications

Alternative Packsize

Catalog Number Description
14-647M SGK3 Protein, active, 250 µg

Product Families

Categories

Life Science Research > Proteins and Enzymes > Purified Kinases
Life Science Research > Drug Discovery and Development > Kinase & Phosphatase Screening > Purified Kinases