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581500 TEMPOL - CAS 2226-96-2 - Calbiochem

A stable, cell-permeable nitroxide that acts as a free radical scavenger and nitric oxide spin trap.

TEMPOL - CAS 2226-96-2 - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: 4-Hydroxy-TEMPO, 4-Hydroxy-2,2,6,6-tetramethylpiperidine-1-oxyl

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Overview

Replacement Information

Key Specifications Table

CAS #Empirical Formula
2226-96-2C₉H₁₈NO₂

Products

Catalog NumberPackaging Qty/Pack
581500-500MG Plastic ampoule 500 mg
Description
OverviewA stable, cell-permeable nitroxide that acts as a free radical scavenger and nitric oxide spin trap. Induces oxidative stress and enhances the levels of p21WAF1 in HL-60 cells in a dose-dependent manner. Reported to reduce organ injury following hemorrhagic shock. Exhibits radio-protective and anti-proliferative properties.
Catalogue Number581500
Brand Family Calbiochem®
Synonyms4-Hydroxy-TEMPO, 4-Hydroxy-2,2,6,6-tetramethylpiperidine-1-oxyl
References
ReferencesGariboldi, M.B., et al. 2000. Free Radic. Biol. Med. 29, 633.
Miura, Y., et al. 2000. J. Radiat. Res. (Tokyo) 41, 103.
Mota-Filipe, H., et al. 1999. Shock 12, 255.
Product Information
CAS number2226-96-2
ATP CompetitiveN
FormOrange powder or crystals
Hill FormulaC₉H₁₈NO₂
Chemical formulaC₉H₁₈NO₂
ReversibleN
Structure formula ImageStructure formula Image
Quality LevelMQ100
Applications
Biological Information
Primary TargetFree radical scavenger and nitric oxide spin trap
Purity≥97% by nitrogen content
Physicochemical Information
Cell permeableY
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
RTECSTN8991000
Safety Information
R PhraseR: 22-41

Harmful if swallowed.
Risk of serious damage to eyes.
S PhraseS: 39-26

Wear eye/face protection.
In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Harmful
Storage -20°C
Protect from Light Protect from light
Do not freeze Ok to freeze
Special InstructionsPrepare fresh solutions. Following reconstitution, aliquot and freeze (-20°C).
Packaging Information
Packaged under inert gas Packaged under inert gas
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalog Number GTIN
581500-500MG 04055977265620

Documentation

TEMPOL - CAS 2226-96-2 - Calbiochem SDS

Title

Safety Data Sheet (SDS) 

TEMPOL - CAS 2226-96-2 - Calbiochem Certificates of Analysis

TitleLot Number
581500

References

Reference overview
Gariboldi, M.B., et al. 2000. Free Radic. Biol. Med. 29, 633.
Miura, Y., et al. 2000. J. Radiat. Res. (Tokyo) 41, 103.
Mota-Filipe, H., et al. 1999. Shock 12, 255.

Brochure

Title
Pathways and Biomarkers of Oxidative Stress
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision29-June-2018 JSW
Synonyms4-Hydroxy-TEMPO, 4-Hydroxy-2,2,6,6-tetramethylpiperidine-1-oxyl
DescriptionA stable, cell-permeable nitroxide free radical that acts as a radical scavenger and nitric oxide spin trap. Induces oxidative stress and enhances the levels of p21WAF1 in HL-60 cells in a dose-dependent manner. Reported to reduce organ injury following hemorrhagic shock. Exhibits radio-protective and anti-proliferative properties.
FormOrange powder or crystals
Intert gas (Yes/No) Packaged under inert gas
CAS number2226-96-2
RTECSTN8991000
Chemical formulaC₉H₁₈NO₂
Structure formulaStructure formula
Purity≥97% by nitrogen content
SolubilityDMSO (5 mg/ml), ethanol, or H₂O
Storage Protect from light
-20°C
Do Not Freeze Ok to freeze
Special InstructionsPrepare fresh solutions. Following reconstitution, aliquot and freeze (-20°C).
Toxicity Harmful
ReferencesGariboldi, M.B., et al. 2000. Free Radic. Biol. Med. 29, 633.
Miura, Y., et al. 2000. J. Radiat. Res. (Tokyo) 41, 103.
Mota-Filipe, H., et al. 1999. Shock 12, 255.