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605225 Thrombospondin, Human Platelets

Thrombospondin, Human Platelets MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
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605225
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Overview

Replacement Information

Products

Catalog NumberPackaging Qty/Pack
605225-25UG Plastic ampoule 25 μg
Description
OverviewNative thrombospondin purified from human platelets. Adhesive glycoprotein released in response to platelet activation by α-thrombin. An angiogenesis inhibitor that blocks the FGF-induced neovascularization of the rat cornea. An inducer of platelet aggregation. Synthesized by a number of different cells and secreted into the extracellular matrix. Involved in the regulation of cellular proliferation.
Catalogue Number605225
Brand Family Calbiochem®
References
ReferencesArmstrong, L.C., et al. 2002. Mol. Biol. Cell 13, 1893.
Michaund, M. and Poyet, O. 1994. Anticancer Res. 14, 1127.
Castle, V.P., et al. 1993. J. Biol. Chem. 268, 2899.
Koch, A.E., et al. 1993. Pathobiology 61, 1.
Tolsma, S.S., et al. 1993. J. Cell Biol. 122, 497.
Tuszynski, G.P., et al. 1993. J. Cell Biol. 120, 513.
Schon, P., et al. 1992. Eur. J. Cell Biol. 59, 329.
Good, D.J., et al. 1990. Proc. Natl. Acad. Sci. USA 87, 6624.
Product Information
FormLyophlized
FormulationLyophilized from 600 mM NaCl, 20 mM Tris, 1 mM CaCl₂, 20% sucrose, pH 7.8.
Quality LevelMQ100
Applications
Biological Information
Purity≥95% by SDS-PAGE
SourcePrepared from platelets that have been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Blue Ice Only
Toxicity Standard Handling
Storage ≤ -70°C
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-70°C) for long-term storage or refrigerate (4°C) for short-term storage. Stock solutions are stable for 1 week at 4°C or for at least 1 month at -70°C. Product is extremely adherent to surfaces; keep frozen (-70°C) before use and use siliconized surfaces to insure product recovery.
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalog Number GTIN
605225-25UG 04055977188486

Documentation

Thrombospondin, Human Platelets SDS

Title

Safety Data Sheet (SDS) 

Thrombospondin, Human Platelets Certificates of Analysis

TitleLot Number
605225

References

Reference overview
Armstrong, L.C., et al. 2002. Mol. Biol. Cell 13, 1893.
Michaund, M. and Poyet, O. 1994. Anticancer Res. 14, 1127.
Castle, V.P., et al. 1993. J. Biol. Chem. 268, 2899.
Koch, A.E., et al. 1993. Pathobiology 61, 1.
Tolsma, S.S., et al. 1993. J. Cell Biol. 122, 497.
Tuszynski, G.P., et al. 1993. J. Cell Biol. 120, 513.
Schon, P., et al. 1992. Eur. J. Cell Biol. 59, 329.
Good, D.J., et al. 1990. Proc. Natl. Acad. Sci. USA 87, 6624.
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision19-May-2008 RFH
DescriptionNative thrombospondin purified from human platelets. Adhesive glycoprotein released in response to platelet activation by a-thrombin. Inhibits FGF-induced neovascularization on rat cornea. An inducer of platelet aggregation. Synthesized by a number of cells and secreted into the extracellular matrix. Involved in the regulation of cellular proliferation.
FormLyophlized
FormulationLyophilized from 600 mM NaCl, 20 mM Tris, 1 mM CaCl₂, 20% sucrose, pH 7.8.
SourcePrepared from platelets that have been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.
Purity≥95% by SDS-PAGE
SolubilityH₂O. Please refer to lot-specific reconstitution volume on the vial label.
Storage ≤ -70°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-70°C) for long-term storage or refrigerate (4°C) for short-term storage. Stock solutions are stable for 1 week at 4°C or for at least 1 month at -70°C. Product is extremely adherent to surfaces; keep frozen (-70°C) before use and use siliconized surfaces to insure product recovery.
Toxicity Standard Handling
Merck USA index14 9387
ReferencesArmstrong, L.C., et al. 2002. Mol. Biol. Cell 13, 1893.
Michaund, M. and Poyet, O. 1994. Anticancer Res. 14, 1127.
Castle, V.P., et al. 1993. J. Biol. Chem. 268, 2899.
Koch, A.E., et al. 1993. Pathobiology 61, 1.
Tolsma, S.S., et al. 1993. J. Cell Biol. 122, 497.
Tuszynski, G.P., et al. 1993. J. Cell Biol. 120, 513.
Schon, P., et al. 1992. Eur. J. Cell Biol. 59, 329.
Good, D.J., et al. 1990. Proc. Natl. Acad. Sci. USA 87, 6624.