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108386 Tris(hydroxymethyl)aminomethane

(Trometamol) EMPROVE® EXPERT Ph Eur,BP,ChP,JPC,USP

Tris(hydroxymethyl)aminomethane MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: Trometamol, Aminomethylidine trimethanol, 2-Amino-2-hydroxymethyl-1.3-propanediol, TRIS-buffer

CAS #: 77-86-1 EC Number: 201-064-4 Molar Mass: 121.14 g/mol Chemical Formula: H₂NC(CH₂OH)₃ Hill Formula: C₄H₁₁NO₃ Grade: Ph Eur,BP,ChP,JPC,USP
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Overview

Replacement Information

Key Specifications Table

CAS #EC NumberHill FormulaChemical FormulaMolar MassGrade Value
77-86-1201-064-4C₄H₁₁NO₃H₂NC(CH₂OH)₃121.14 g/molPh Eur,BP,ChP,JPC,USP

Products

Catalog NumberPackaging Qty/Pack
1.08386.1000 Plastic bottle 1 kg
1083865000 Plastic bottle 5 kg
1083869013 Bucket, plastic 12 kg
1083869025 25 kg
Description
Catalogue Number108386
SynonymsTrometamol, Aminomethylidine trimethanol, 2-Amino-2-hydroxymethyl-1.3-propanediol, TRIS-buffer
DescriptionTris(hydroxymethyl)aminomethane
References
Product Information
CAS number77-86-1
EC number201-064-4
GradePh Eur,BP,ChP,JPC,USP
Hill FormulaC₄H₁₁NO₃
Chemical formulaH₂NC(CH₂OH)₃
Molar Mass121.14 g/mol
HS Code2922 19 99
Structure formula ImageStructure formula Image
Quality LevelMQ500
Applications
Biological Information
Physicochemical Information
Boiling point219 - 220 °C (13.3 hPa)
Density1.32 g/cm3 (20 °C)
Melting Point169 °C
pH value10.2 - 10.6 (6 g/l, H₂O, 20 °C)
Vapor pressure<0.1 hPa (20 °C)
Bulk density840 kg/m3
Solubility678 g/l
Dimensions
Materials Information
Toxicological Information
LD 50 oralLD50 Rat > 5000 mg/kg
LD 50 dermalLD50 Rat > 5000 mg/kg
Safety Information according to GHS
RTECSTY2900000
Storage class10 - 13 Other liquids and solids
WGKWGK 1 slightly hazardous to water
Disposal3
Relatively unreactive organic reagents should be collected in container A. If halogenated, they should be collected in container B. For solid residues use container C.
Safety Information
Product Usage Statements
Storage and Shipping Information
StorageNoTempLimit
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalog Number GTIN
1.08386.1000 04022536103846
1083865000 04022536775487
1083869013 04027269174378
1083869025 04022536103853

Documentation

Material Qualification Dossier

TitleVersion
6.0

Quality Management Dossier (Open Access)

Title

Operational Excellence Dossier

Title

Tris(hydroxymethyl)aminomethane SDS

Title

Safety Data Sheet (SDS) 

Tris(hydroxymethyl)aminomethane Certificates of Analysis

Product Number PackagingSpecificationLot Number
1.08386.1000 Plastic bottlePDF Specification Document
1083865000 Plastic bottlePDF Specification Document
1083869013 Bucket, plasticPDF Specification Document
1083869025 PDF Specification Document

Certificates

Title

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Categories

Biopharmaceutical Manufacturing > Downstream Processing > Chromatography > Process Chemicals > Buffers
Small Molecule Pharmaceuticals > Formulation > Semisolid Dosage Form > Acidulants and pH Adjustments
Biopharmaceutical Manufacturing > Formulation > Liquid Dosage > pH Adjustments and Isotonizers
Small Molecule Pharmaceuticals > Formulation > Liquid Dosage Form > pH Adjustments and Isotonizers