Millipore Sigma Vibrant Logo
Attention: We have moved. EMD Millipore products are no longer available for purchase on emdmillipore.com.Learn More

672999 V-ATPase Inhibitor, KM91104 - Calbiochem

V-ATPase Inhibitor, KM91104 - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: H+-ATPase Inhibitor

View Products on Sigmaaldrich.com
672999
Purchase on Sigma-Aldrich

Overview

Replacement Information

Key Specifications Table

Empirical Formula
C₁₄H₁₂N₂O₄

Products

Catalog NumberPackaging Qty/Pack
672999-10MG Glass bottle 10 mg
Description
OverviewA cell-permeable, non-macrolide small molecule V-ATPase inhibitor that specifically targets the a3-b2 subunit protein protein interation of V-ATPase (IC50 of 2.3 µM), in vitro. It is also shown to inhibit osteoclast resorption (IC50 of 1.2 µM) on both synthetic hydroxyapatite surfaces and dentin slices in an in vitro osteoclast model, RANKL-differentiated RAW 264.7 cells, without significantly affecting RAW 264.7 cell viability or RANKL-mediated osteoclast differentiation.
Catalogue Number672999
Brand Family Calbiochem®
SynonymsH+-ATPase Inhibitor
References
ReferencesKartner, N., et al. 2010. J. Biol. Chem. 285, 37476.
Product Information
FormOff-white solid
Hill FormulaC₁₄H₁₂N₂O₄
Chemical formulaC₁₄H₁₂N₂O₄
Structure formula ImageStructure formula Image
Quality LevelMQ100
Applications
Biological Information
Purity>98% by HPLC
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Shipped with Blue Ice or with Dry Ice
Toxicity Standard Handling
Storage -20°C
Protect from Light Protect from light
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Packaging Information
Packaged under inert gas Packaged under inert gas
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalog Number GTIN
672999-10MG 04055977184143

Documentation

V-ATPase Inhibitor, KM91104 - Calbiochem SDS

Title

Safety Data Sheet (SDS) 

V-ATPase Inhibitor, KM91104 - Calbiochem Certificates of Analysis

TitleLot Number
672999

References

Reference overview
Kartner, N., et al. 2010. J. Biol. Chem. 285, 37476.
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision28-April-2015 JSW
SynonymsH+-ATPase Inhibitor
DescriptionA cell-permeable, non-macrolide small molecule V-ATPase inhibitor that specifically targets the a3-b2 subunit protein protein interation of V-ATPase (IC50 of 2.3 µM), in vitro. It is also shown to inhibit osteoclast resorption (IC50 of 1.2 µM) on both synthetic hydroxyapatite surfaces and dentin slices in an in vitro osteoclast model, RANKL-differentiated RAW 264.7 cells, without significantly affecting RAW 264.7 cell viability or RANKL-mediated osteoclast differentiation.
FormOff-white solid
Intert gas (Yes/No) Packaged under inert gas
Chemical formulaC₁₄H₁₂N₂O₄
Structure formulaStructure formula
Purity>98% by HPLC
SolubilityDMSO (100 mg/ml)
Storage Protect from light
-20°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Toxicity Standard Handling
ReferencesKartner, N., et al. 2010. J. Biol. Chem. 285, 37476.