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676491 VEGF Inducer, GS4012 - CAS 328073-92-3 - Calbiochem

A cell-permeable pyridinyl-thioether compound that acts as a potent inducer of VEGF and VEGF-mediated vessel formation.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: 4-(2-(4-Methoxyphenylsulfanyl)ethyl)pyridine, HCl, GS4012

Primary Target: Potent inducer of VEGF and VEGF-mediated vessel formation
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Overview

Replacement Information

Key Specifications Table

CAS #Empirical Formula
328073-92-3C₁₄H₁₅NOS • HCl

Products

Catalog NumberPackaging Qty/Pack
676491-10MG Plastic ampoule 10 mg
Description
OverviewA cell-permeable pyridinyl-thioether compound that acts as a potent inducer of VEGF and VEGF-mediated vessel formation. GS4012-induced upregulation of VEGF correlates well with its ability to suppress the gridlock/coarctation phenotype (7.5 µg/ml) in Zebrafish and to stimulate tubule network formation (5 µg/ml) in HUVECs.
Catalogue Number676491
Brand Family Calbiochem®
Synonyms4-(2-(4-Methoxyphenylsulfanyl)ethyl)pyridine, HCl, GS4012
References
ReferencesPeterson, R.T., et al. 2004. Nat. Biotechnol. 22, 595.
Depre, C., et al. 2003. Circulation 108, 2723.
Product Information
CAS number328073-92-3
ATP CompetitiveN
FormWhite solid
Hill FormulaC₁₄H₁₅NOS • HCl
Chemical formulaC₁₄H₁₅NOS • HCl
Hygroscopic Hygroscopic
ReversibleN
Structure formula ImageStructure formula Image
Quality LevelMQ100
Applications
Biological Information
Primary TargetPotent inducer of VEGF and VEGF-mediated vessel formation
Purity≥95% by HPLC
Physicochemical Information
Cell permeableY
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
Toxicity Standard Handling
Storage +2°C to +8°C
Protect from Light Protect from light
Hygroscopic Hygroscopic
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
Packaging Information
Packaged under inert gas Packaged under inert gas
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalog Number GTIN
676491-10MG 04055977183672

Documentation

VEGF Inducer, GS4012 - CAS 328073-92-3 - Calbiochem SDS

Title

Safety Data Sheet (SDS) 

VEGF Inducer, GS4012 - CAS 328073-92-3 - Calbiochem Certificates of Analysis

TitleLot Number
676491

References

Reference overview
Peterson, R.T., et al. 2004. Nat. Biotechnol. 22, 595.
Depre, C., et al. 2003. Circulation 108, 2723.
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision30-October-2023 JSW
Synonyms4-(2-(4-Methoxyphenylsulfanyl)ethyl)pyridine, HCl, GS4012
DescriptionA cell-permeable and potent inducer of VEGF and VEGF-mediated blood vessel formation. GS4012-induced upregulation of VEGF correlates with its ability to suppress the gridlock/coarctation phenotype (7.5 µg/ml) in Zebrafish and to stimulate tubule network formation (5 µg/ml) in HUVECs. An essential molecule required during angioblasts cell fate determination.
FormWhite solid
Intert gas (Yes/No) Packaged under inert gas
CAS number328073-92-3
Chemical formulaC₁₄H₁₅NOS • HCl
Structure formulaStructure formula
Purity≥95% by HPLC
SolubilityDMSO (200 mg/ml), water, or Methanol (50 mg/ml)
Storage Protect from light
+2°C to +8°C
Hygroscopic
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
Toxicity Standard Handling
ReferencesPeterson, R.T., et al. 2004. Nat. Biotechnol. 22, 595.
Depre, C., et al. 2003. Circulation 108, 2723.