681664 Sigma-AldrichWnt Agonist I in DMSO - CAS 853220-52-7 - Calbiochem
The Wnt Agonist I in DMSO, also referenced under CAS 853220-52-7, controls the biological activity of Wnt. This small molecule/inhibitor is primarily used for Cancer applications.
More>> The Wnt Agonist I in DMSO, also referenced under CAS 853220-52-7, controls the biological activity of Wnt. This small molecule/inhibitor is primarily used for Cancer applications. Less<<MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Synonyms: Wnt Pathway Activator I in DMSO, 2-Amino-4-(3,4-(methylenedioxy)benzylamino)-6-(3-methoxyphenyl)pyrimidine
Recommended Products
Overview
| Replacement Information |
|---|
Key Specifications Table
| CAS # | Empirical Formula |
|---|---|
| 853220-52-7 | C₁₉H₁₈N₄O₃ |
Products
| Catalog Number | Packaging | Qty/Pack | |
|---|---|---|---|
| 681664-2MG | Glass bottle | 2 mg |
| Description | |
|---|---|
| Overview | A cell-permeable, potent, and selective activator of Wnt signaling that does not inhibit the activity of GSK-3β (IC50 >60 µM). Shown to mimic the effect of Wnt and induce β-catenin and TCF (T-cell fate)-dependent transcriptional activity (EC50 = 700 nM in HEK-293T cells). Reported to cause substantial head defects during Xenopus embryonic development. The solid form of this compound (Cat. No. 681665) is also available. |
| Catalogue Number | 681664 |
| Brand Family | Calbiochem® |
| Synonyms | Wnt Pathway Activator I in DMSO, 2-Amino-4-(3,4-(methylenedioxy)benzylamino)-6-(3-methoxyphenyl)pyrimidine |
| References | |
|---|---|
| References | Liu, J., et al. 2005. Angew. Chem. Int. Ed. 44, 1987. |
| Product Information | |
|---|---|
| CAS number | 853220-52-7 |
| Form | Liquid |
| Formulation | A 25 mM (2 mg/228 µL) solution of Wnt Agonist I (Cat. No. 681665) in DMSO. |
| Hill Formula | C₁₉H₁₈N₄O₃ |
| Hygroscopic | Hygroscopic |
| Reversible | Y |
| Structure formula Image | |
| Quality Level | MQ100 |
| Applications |
|---|
| Biological Information | |
|---|---|
| Purity | ≥95% by HPLC |
| Physicochemical Information | |
|---|---|
| Cell permeable | Y |
| Dimensions |
|---|
| Materials Information |
|---|
| Toxicological Information |
|---|
| Safety Information according to GHS |
|---|
| Product Usage Statements |
|---|
| Packaging Information | |
|---|---|
| Packaged under inert gas | Packaged under inert gas |
| Transport Information |
|---|
| Supplemental Information |
|---|
| Specifications |
|---|
| Global Trade Item Number | |
|---|---|
| Catalog Number | GTIN |
| 681664-2MG | 04055977260229 |
Documentation
Wnt Agonist I in DMSO - CAS 853220-52-7 - Calbiochem SDS
| Title |
|---|
Wnt Agonist I in DMSO - CAS 853220-52-7 - Calbiochem Certificates of Analysis
| Title | Lot Number |
|---|---|
| 681664 |
References
| Reference overview |
|---|
| Liu, J., et al. 2005. Angew. Chem. Int. Ed. 44, 1987. |
| Data Sheet | ||||||||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.
|