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508508 Zonisamide - CAS 68291-97-4 - Calbiochem

An antiepileptic agent that blocks voltage-dependent Na(+) channels and T-type Ca(2+) channels.

Zonisamide - CAS 68291-97-4 - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: AD 810, CI 912

Primary Target: Na+ and Ca2+ channels
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Overview

Replacement Information

Key Specifications Table

CAS #Empirical Formula
68291-97-4C₈H₈N₂O₃S

Products

Catalog NumberPackaging Qty/Pack
5.08508.0001 Glass bottle 10 mg
Description
OverviewA benzisoxazole derivative that acts as an antiepileptic agent and is shown to block voltage-dependent Na(+) channels and T-type Ca(2+) channels. However, it does not serve as anticonvulsant agent in chemically induced seizures in flurothyl and pentetrazole models. Acts as an inhibitor of monoamine oxidase B (MAO-B; IC50 = 24.8 µM). Displays neurprotective properties.

Please note that the molecular weight for this compound is batch-specific due to variable water content.
Catalogue Number508508
Brand Family Calbiochem®
SynonymsAD 810, CI 912
References
ReferencesSonsalla, P.K., et al. 2010. Exp. Neurol. 221, 329.
Sobieszek, G. et al. 2003. Pol. J. Pharmacol. 55, 68.
Product Information
CAS number 68291-97-4
FormWhite solid
Hill FormulaC₈H₈N₂O₃S
Chemical formulaC₈H₈N₂O₃S
Structure formula ImageStructure formula Image
Quality LevelMQ100
Applications
Biological Information
Primary TargetNa+ and Ca2+ channels
Purity≥98% by HPLC
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
R PhraseR: 22

Harmful if swallowed.
S PhraseS: 36/37/39-45-46

Wear suitable protective clothing, gloves and eye/face protection.
In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).
If swallowed, seek medical advice immediately and show this container or label.
Product Usage Statements
Storage and Shipping Information
Ship Code Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
Toxicity Harmful
Storage +2°C to +8°C
Protect from Light Protect from light
Do not freeze Ok to freeze
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalog Number GTIN
5.08508.0001 04055977262018

Documentation

Zonisamide - CAS 68291-97-4 - Calbiochem SDS

Title

Safety Data Sheet (SDS) 

References

Reference overview
Sonsalla, P.K., et al. 2010. Exp. Neurol. 221, 329.
Sobieszek, G. et al. 2003. Pol. J. Pharmacol. 55, 68.
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision31-January-2014 JSW
SynonymsAD 810, CI 912
DescriptionA benzisoxazole derivative that acts as an antiepileptic agent and is shown to block voltage-dependent Na(+) channels and T-type Ca(2+) channels. However, it does not serve as anticonvulsant agent in chemically induced seizures in flurothyl and pentetrazole models. Acts as an inhibitor of monoamine oxidase B (MAO-B; IC50 = 24.8 µM). Displays neurprotective properties.
FormWhite solid
CAS number 68291-97-4
Chemical formulaC₈H₈N₂O₃S
Structure formulaStructure formula
Purity≥98% by HPLC
Storage Protect from light
+2°C to +8°C
Do Not Freeze Ok to freeze
Toxicity Harmful
ReferencesSonsalla, P.K., et al. 2010. Exp. Neurol. 221, 329.
Sobieszek, G. et al. 2003. Pol. J. Pharmacol. 55, 68.