Postsynaptic Receptors

The postsynaptic effect of neurotransmitter release from the presynaptic terminal depends on a specific protein receptor complex. This specific synaptic receptor pharmacology defines the function of many neurons and neuroendocrine cell targets in both the peripheral and central nervous system. Antibody targets to specific peri-synaptic ionotropic or metabotropic receptors can be used to identify and localize particular postsynaptic neuronal targets.