Our broad portfolio consists of multiplex panels that allow you to choose, within the panel, analytes that best meet your needs. On a separate tab you can choose the premixed cytokine format or a single plex kit.
Cell Signaling Kits & MAPmates™
Choose fixed kits that allow you to explore entire pathways or processes. Or design your own kits by choosing single plex MAPmates™, following the provided guidelines.
The following MAPmates™ should not be plexed together:
-MAPmates™ that require a different assay buffer
-Phospho-specific and total MAPmate™ pairs, e.g. total GSK3β and GSK3β (Ser 9)
-PanTyr and site-specific MAPmates™, e.g. Phospho-EGF Receptor and phospho-STAT1 (Tyr701)
-More than 1 phospho-MAPmate™ for a single target (Akt, STAT3)
-GAPDH and β-Tubulin cannot be plexed with kits or MAPmates™ containing panTyr
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To begin designing your MILLIPLEX® MAP kit select a species, a panel type or kit of interest.
Custom Premix Selecting "Custom Premix" option means that all of the beads you have chosen will be premixed in manufacturing before the kit is sent to you.
If you have chosen panel analytes and then choose a premix or single plex kit, you will lose that customization.
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48-602MAG
Buffer Detection Kit for Magnetic Beads
1 Kit
Space Saver Option Customers purchasing multiple kits may choose to save storage space by eliminating the kit packaging and receiving their multiplex assay components in plastic bags for more compact storage.
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504472
Sigma-Aldrich(2R,4R)-APDC - CAS 169209-63-6 - Calbiochem
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Description
Overview
A highly selective and potent agonist for group II metabotropic glutamate receptor (EC50 = 0.4, 0.4, > 100, > 100, > 300 and > 300 µM for human mGlu2, mGlu3, mGlu1, mGlu5, mGlu4 and mGlu7 receptors respectively). Used as anti- and pro-convulsant, neuroprotectant, antinociceptive, and addiction treatment.
Folbergrová, J., et al. 2005. Experimental Neurology.192, 420. Fisher, K., et al. 2002. Pharmacol. Bioche. and Behav.73, 411. Schoepp, D., et al. 1995. Neuropharmacology.34, 843. Monn, J., et al. 1996. J. Med. Chem.39, 2990.
Product Information
CAS number
169209-63-6
Form
Off-white powder
Hill Formula
C₆H₁₀N₂O₄
Chemical formula
C₆H₁₀N₂O₄
Structure formula Image
Applications
Biological Information
Primary Target
mGlu₂ and mGlu₃
Purity
≥98% by HPLC
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code
Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
Toxicity
Standard Handling
Storage
+2°C to +8°C
Protect from Light
Protect from light
Do not freeze
Ok to freeze
Special Instructions
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Folbergrová, J., et al. 2005. Experimental Neurology.192, 420. Fisher, K., et al. 2002. Pharmacol. Bioche. and Behav.73, 411. Schoepp, D., et al. 1995. Neuropharmacology.34, 843. Monn, J., et al. 1996. J. Med. Chem.39, 2990.
Data Sheet
Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.
A highly selective and potent agonist for group II metabotropic glutamate receptor (EC50 = 0.4, 0.4, > 100, > 100, > 300 and > 300 µM for human mGlu2, mGlu3, mGlu1, mGlu5, mGlu4 and mGlu7 receptors respectively). Used as anti- and pro-convulsant, neuroprotectant, antinociceptive, and addiction treatment.
Form
Off-white powder
CAS number
169209-63-6
Chemical formula
C₆H₁₀N₂O₄
Structure formula
Purity
≥98% by HPLC
Solubility
H₂O (100 mM)
Storage
Protect from light
+2°C to +8°C
Do Not Freeze
Ok to freeze
Special Instructions
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Toxicity
Standard Handling
References
Folbergrová, J., et al. 2005. Experimental Neurology.192, 420. Fisher, K., et al. 2002. Pharmacol. Bioche. and Behav.73, 411. Schoepp, D., et al. 1995. Neuropharmacology.34, 843. Monn, J., et al. 1996. J. Med. Chem.39, 2990.
