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AB15554-50UL Anti-AT2 Receptor Antibody

This Anti-AT2 Receptor Antibody is validated for use in WB for the detection of AT2 Receptor.

Anti-AT2 Receptor Antibody MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Neuroscience Research Sub-Category: Hormones & Receptors Gene Symbol: AGTR2, MRX88, AT2, ATGR2 UniProt Number: P50052
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AB15554-50UL
50 µL  
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      Key Specifications Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      M, RWBRbAffinity PurifiedPolyclonal Antibody
      Description
      Catalogue NumberAB15554-50UL
      Brand Family Chemicon®
      Trade Name
      • Chemicon
      DescriptionAnti-AT2 Receptor Antibody
      Alternate Names
      • Angiotensin II receptory type 2
      • AGTR2
      References
      Product Information
      FormatAffinity Purified
      HS Code3002 15 90
      Control
      • Included free of charge with the antibody is 40 µg of control antigen (lyophilized powder). The stock solution of the antigen can be made up using 100 µL of sterile deionized water. For negative control, preincubate 1 µg of peptide with 1 µg of antibody for one hour at room temperature. Optimal concentrations must be determined by the end user.
      PresentationLyophilized from phosphate buffered saline, pH 7.4, containing 1% BSA, and 0.025% sodium azide as a preservative. Reconstitute with 50 μL of sterile deionized water. Centrifuge antibody preparation before use (10,000 xg for 5 min).
      Quality LevelMQ100
      Applications
      ApplicationThis Anti-AT2 Receptor Antibody is validated for use in WB for the detection of AT2 Receptor.
      Key Applications
      • Western Blotting
      Application NotesWestern blot: 1:200-1:500 using ECL on rat brain and mouse MS1 cell lysate.
      Dilutions should be made using a carrier protein such as BSA (1-3%).

      Optimal working dilutions must be determined by the end user.
      Biological Information
      ImmunogenPurified peptide from the N-terminus of rat AT2 Receptor (Accession number P35351).
      HostRabbit
      SpecificityRecognizes AT2 Receptor (Angiotensin II receptory type 2, AGTR2).
      Species Reactivity
      • Mouse
      • Rat
      Antibody TypePolyclonal Antibody
      Entrez Gene Number
      Entrez Gene SummaryAngiotensin II is a potent pressor hormone and a primary regulator of aldosterone secretion. It is an important effector controlling blood pressure and volume in the cardiovascular system. It acts through at least two types of receptors termed AT1 and AT2. AGTR2 belongs to a family 1 of G-protein coupled receptors. It is an intergral membrane protein. It plays a role in the central nervous system and cardiovascular functions that are mediated by the renin-angiotensin system. This receptor mediates programmed cell death (apoptosis). In adults, it is highly expressed in myometrium with lower levels in adrenal gland and fallopian tube. It is highly expressed in fetal kidney and intestine. The human AGTR2 gene is composed of three exons and spans at least 5 kb. Exons 1 and 2 encode for 5' untranslated mRNA sequence and exon 3 harbors the entire uninterrupted open reading frame.
      Gene Symbol
      • AGTR2
      • MRX88
      • AT2
      • ATGR2
      Non-Reactive Species
      • Human
      Purification MethodImmunoAffinity Purified
      UniProt Number
      UniProt SummaryFUNCTION: SwissProt: P50052 # Receptor for angiotensin II. Cooperates with MTUS1 to inhibit ERK2 activation and cell proliferation.
      SIZE: 363 amino acids; 41184 Da
      SUBUNIT: Interacts with MTUS1.
      SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.
      TISSUE SPECIFICITY: In adult, highly expressed in myometrium with lower levels in adrenal gland and fallopian tube. Very highly expressed in fetal kidney and intestine.
      SIMILARITY: SwissProt: P50052 ## Belongs to the G-protein coupled receptor 1 family.
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsMaintain lyophilized material at -20°C for up to 12 months after date of receipt. After reconstitution maintain at -20°C in undiluted aliquots for up to 6 months. Avoid repeated freeze/thaw cycles.
      Packaging Information
      Material Size50 µL
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalog Number GTIN
      AB15554-50UL 04053252672163

      Documentation

      Anti-AT2 Receptor Antibody SDS

      Title

      Safety Data Sheet (SDS) 

      Anti-AT2 Receptor Antibody Certificates of Analysis

      TitleLot Number
      RABBIT ANTI-AT2 RECEPTOR AFFINITY PURIFIED POLYCLONAL ANTIBODY - 2145848 2145848
      RABBIT ANTI-AT2 RECEPTOR - 3802618 3802618
      RABBIT ANTI-AT2 RECEPTOR -2709678 2709678
      RABBIT ANTI-AT2 RECEPTOR -2716620 2716620
      RABBIT ANTI-AT2 RECEPTOR -2795474 2795474
      RABBIT ANTI-AT2 RECEPTOR -2799373 2799373
      RABBIT ANTI-AT2 RECEPTOR AFFINITY PURIFIED POLYCLONAL ANTIBODY - 2036676 2036676
      RABBIT ANTI-AT2 RECEPTOR AFFINITY PURIFIED POLYCLONAL ANTIBODY - 2280815 2280815
      RABBIT ANTI-AT2 RECEPTOR AFFINITY PURIFIED POLYCLONAL ANTIBODY - 2326288 2326288

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      Categories

      Life Science Research > Antibodies and Assays > Primary Antibodies