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antibody form
affinity purified immunoglobulin
Quality Level
clone
polyclonal
description
Target: PO, PVN, Purkinje cells, other select regions
species reactivity
human, rabbit
concentration
(Please refer to the Certificate of Analysis for the lot-specific concentration.)
technique(s)
immunohistochemistry: suitable
UniProt accession no.
General description
FUNCTION: SwissProt: Q9H1Y3 # May play a role in encephalic photoreception.
SIZE: 402 amino acids; 44873 Da
SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein.
TISSUE SPECIFICITY: Strongly expressed in brain. Highly expressed in the preoptic area and paraventricular nucleus of the hypothalamus. Shows highly patterned expression in other regions of the brain, being enriched in selected regions of the cerebral cortex, cerebellar Purkinje cells, a subset of striatal neurons, selected thalamic nuclei, and a subset of interneurons in the ventral horn of the spinal cord.
SIMILARITY: SwissProt: Q9H1Y3 ## Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
SIZE: 402 amino acids; 44873 Da
SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein.
TISSUE SPECIFICITY: Strongly expressed in brain. Highly expressed in the preoptic area and paraventricular nucleus of the hypothalamus. Shows highly patterned expression in other regions of the brain, being enriched in selected regions of the cerebral cortex, cerebellar Purkinje cells, a subset of striatal neurons, selected thalamic nuclei, and a subset of interneurons in the ventral horn of the spinal cord.
SIMILARITY: SwissProt: Q9H1Y3 ## Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
Synthetic peptide from the C-terminal domain of human Encephalopsin.
Specificity
Recognizes Encephalopsin.
Application
Immunohistochemistry on paraffin embedded tissue sections.
Optimal working dilutions must be determined by the end user.
Optimal working dilutions must be determined by the end user.
Physical form
Affinity purified immunoglobulin. Liquid in PBS, pH 7.7 with 0.01% sodium azide.
Storage and Stability
Maintain at -70°C in undiluted aliquots for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage Class
10 - Combustible liquids
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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