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CBL85 Anti-Endothelin-1 Antibody, clone IC4

Detect Endothelin-1 using this Anti-Endothelin-1 Antibody, clone IC4 validated for use in IHC.

Anti-Endothelin-1 Antibody, clone IC4 MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Neuroscience Research Sub-Category: CNS Control of Metabolism, Hormones & Receptors Gene Symbol: EDN1, OTTHUMP00000039245, Preproendothelin-1, ET1, PPET1, ET-1, HDLCQ7 UniProt Number: P05305
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CBL85
1 mg  
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      Key Specifications Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      HIHCMPurifiedMonoclonal Antibody
      Description
      Catalogue NumberCBL85
      Brand Family Chemicon®
      Trade Name
      • Chemicon
      DescriptionAnti-Endothelin-1 Antibody, clone IC4
      References
      Product Information
      FormatPurified
      Control
      • Expressed in lung, placental stem villi vessels and in cultured placental vascular smooth muscle cells
      PresentationLiquid in 0.02 M PBS with 0.25 M NaCl, pH 7.6. Contains 0.1% sodium azide.
      Quality LevelMQ100
      Applications
      ApplicationDetect Endothelin-1 using this Anti-Endothelin-1 Antibody, clone IC4 validated for use in IHC.
      Key Applications
      • Immunohistochemistry
      Application NotesDevelopment of Immunoradiometric assay (IRMA) for endothelin ET-1 which as a circulating plasma peptide has been associated with a variety of disease studies such as diabetes, hypertension, cardiogenic shock, acute myocardial infarction and uraemia.

      Suitable for immunohistochemistry on frozen sections

      Optimal working dilutions must be determined by the end user.
      Biological Information
      CloneIC4
      ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
      HostMouse
      SpecificityRecognizes endothelin ET-1 (10% cross-reactivity with ET-3) and when used in conjunction with CBL87 (anti-endothelin C-terminus) has a sensitivity of 0.06 pmol/L for ET-1.
      IsotypeIgG1
      Species Reactivity
      • Human
      Antibody TypeMonoclonal Antibody
      Entrez Gene Number
      Gene Symbol
      • EDN1
      • OTTHUMP00000039245
      • Preproendothelin-1
      • ET1
      • PPET1
      • ET-1
      • HDLCQ7
      Purification MethodProtein A Purfied
      UniProt Number
      UniProt SummaryFUNCTION: SwissProt: P05305 # Endothelins are endothelium-derived vasoconstrictor peptides.
      SIZE: 212 amino acids; 24425 Da
      SUBCELLULAR LOCATION: Secreted.
      TISSUE SPECIFICITY: Expressed in lung, placental stem villi vessels and in cultured placental vascular smooth muscle cells.
      SIMILARITY: SwissProt: P05305 ## Belongs to the endothelin/sarafotoxin family.
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsFor use within 1 month of purchase when stored at +4°C, for long-term storage, aliquot antibody into small volumes and store at -20°C.
      Packaging Information
      Material Size1 mg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalog Number GTIN
      CBL85 04053252336560

      Documentation

      Anti-Endothelin-1 Antibody, clone IC4 SDS

      Title

      Safety Data Sheet (SDS) 

      Anti-Endothelin-1 Antibody, clone IC4 Certificates of Analysis

      TitleLot Number
      MOUSE ANTI-HUMAN ENDOTHELIN 1 MONOCLONAL ANTIBODY 2919594
      MOUSE ANTI-HUMAN ENDOTHELIN 1 MONOCLONAL ANTIBODY 2924643
      MOUSE ANTI-HUMAN ENDOTHELIN 1 MONOCLONAL ANTIBODY 2979566
      MOUSE ANTI-HUMAN ENDOTHELIN 1 MONOCLONAL ANTIBODY 2953795
      MOUSE ANTI-HUMAN ENDOTHELIN 1 MONOCLONAL ANTIBODY 2953796
      MOUSE ANTI-HUMAN ENDOTHELIN 1 MONOCLONAL ANTIBODY 3102352
      MOUSE ANTI-HUMAN ENDOTHELIN 1 MONOCLONAL ANTIBODY - 2441921 2441921
      MOUSE ANTI-HUMAN ENDOTHELIN 1 MONOCLONAL ANTIBODY - 2455690 2455690
      MOUSE ANTI-HUMAN ENDOTHELIN 1 MONOCLONAL ANTIBODY - 2274267 2274267
      MOUSE ANTI-HUMAN ENDOTHELIN 1 MONOCLONAL ANTIBODY - 2299128 2299128
      Show more

      Data Sheet

      Title
      MOUSE ANTI-HUMAN ENDOTHELIN 1 MONOCLONAL ANTIBODY

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      Categories

      Life Science Research > Antibodies and Assays > Primary Antibodies