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07-1401-AF647 Anti-GLUT-1 Antibody, CT, Alexa Fluor® 647 Conjugate

This Anti-GLUT-1 Antibody, CT, Alexa Fluor® 647 Conjugate is validated for use in Immunocytochemistry for the detection of GLUT-1.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Signaling Research Sub-Category: Developmental Signaling Gene Symbol: SLC2A1, GLUT1 UniProt Number: P11166
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07-1401-AF647
100 µL  
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      Overview

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      Key Specifications Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      H, M, RICCRbAlexaFluor®647Polyclonal Antibody
      Description
      Catalogue Number07-1401-AF647
      DescriptionAnti-GLUT-1 Antibody, CT, Alexa Fluor® 647 Conjugate
      Alternate Names
      • Solute carrier family 2, facilitated glucose transporter member 1
      • Glucose transporter type 1, erythrocyte/brain
      • GLUT-1
      • HepG2 glucose transporter
      • GLUT-1, CT, Alexa Fluor® 488 Conjugate
      Background InformationSolute carrier family 2, facilitated glucose transporter member 1 (UniProt P11166; also known as Glucose transporter type 1 erythrocyte/brain, GLUT-1, HepG2 glucose transporter, Human T-cell leukemia virus I and II receptor, Receptor for HTLV-1 and HTLV-2) is encoded by the SLC2A1 (also known as DYT9, DYT17, DYT18, EIG12, GLUT, GLUT1, HTLVR, GLUT1DS, PED) gene (Gene ID 6513) in human. Glucose transporters (GLUT-1 to GLUT-7) constitute a family of integral membrane glycoproteins that facilitate cellular glucose uptake. In addition to mediateing glucose uptake in adult tissues, GLUT-1 is the predominant glucose transporter in embryonic and fetal tissues. Two forms of GLUT-1 are found in human frontal cortex, the 55 kDa form of GLUT1 regulates import of glucose from blood to brain across the endothelial cells of the blood-brain barrier (BBB), whereas the 45 kDa form of GLUT1 predominantly regulates nonvascular glial glucose uptake.
      References
      Product Information
      FormatAlexaFluor®647
      PresentationPurified rabbit conjugate antibody in PBS with 15 mg/ml BSA and 0.1% sodium azide
      Quality LevelMQ100
      Applications
      ApplicationThis Anti-GLUT-1 Antibody, CT, Alexa Fluor® 647 Conjugate is validated for use in Immunocytochemistry for the detection of GLUT-1.
      Key Applications
      • Immunocytochemistry
      Application NotesImmunocytochemistry Analysis: A 1:100 dilution from a representative lot detected GLUT-1 in HeLa and NIH/3T3 cells.
      The unconjugated antibody (Cat. No. 07-1401) is shown to be suitable also for ELISA, Western blotting, immunocytochemistry, and immunohistochemistry applications.
      Biological Information
      ImmunogenSynthetic peptide corresponding amino acids with the C-terminus of human GLUT-1 coupled to KLH (C-ELFHPLGADSQV).
      EpitopeC-terminus
      ConcentrationPlease refer to lot specific datasheet.
      HostRabbit
      SpecificityThis antibody recognizes GLUT-1.
      Species Reactivity
      • Human
      • Mouse
      • Rat
      Species Reactivity NoteHuman, Mouse, Rat. Predicted to react with Bovine, Feline, Porcine, Equine, Monkey based on 100% sequence homology.
      Antibody TypePolyclonal Antibody
      Entrez Gene Number
      Gene Symbol
      • SLC2A1
      • GLUT1
      Purification MethodAffinity Purfied
      UniProt Number
      Molecular Weight~54 kDa observed
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Immunocytochemistry in A431 cells.

      Immunocytochemistry Analysis: A 1:100 dilution of this antibody detected GLUT-1 in A431 cells.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Packaging Information
      Material Size100 µL
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalog Number GTIN
      07-1401-AF647 04055977296518

      Documentation

      Anti-GLUT-1 Antibody, CT, Alexa Fluor® 647 Conjugate SDS

      Title

      Safety Data Sheet (SDS) 

      Anti-GLUT-1 Antibody, CT, Alexa Fluor® 647 Conjugate Certificates of Analysis

      TitleLot Number
      Anti-GLUT-1, CT, Alexa Fluor® 647 Conjugate 3021918
      Anti-GLUT-1, CT, Alexa Fluor® 647 Conjugate 2901496
      Anti-GLUT-1, CT, Alexa Fluor® 647 Conjugate 2966302
      Anti-GLUT-1, CT, Alexa Fluor® 647 Conjugate - 3605454 3605454
      Anti-GLUT-1, CT, Alexa Fluor® 647 Conjugate - 3883583 3883583
      Anti-GLUT-1, CT, Alexa Fluor® 647 Conjugate - 3923527 3923527
      Anti-GLUT-1, CT, Alexa Fluor® 647 Conjugate - 4090082 4090082
      Anti-GLUT-1, CT, Alexa Fluor® 647 Conjugate -Q2614589 Q2614589