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MABN371 Anti-KChIP2 potassium channel subunit Antibody, clone 60/73

This Anti-KChIP2 potassium channel subunit Antibody, clone 60/73 is validated for use in western blotting & IHC for the detection of KChIP2 potassium channel subunit.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Neuroscience Research Sub-Category: Developmental Signaling Gene Symbol: Kcnip2, Kchip2 UniProt Number: Q9JM59
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MABN371
100 µg  
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      Overview

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      Key Specifications Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      M, R, HWB, IHCMPurifiedMonoclonal Antibody
      Description
      Catalogue NumberMABN371
      DescriptionAnti-KChIP2 potassium channel subunit Antibody, clone 60/73
      Alternate Names
      • Kv channel-interacting protein 2
      • KChIP2
      • A-type potassium channel modulatory protein 2
      • Potassium channel-interacting protein 2
      Background InformationKCHIP2, also known as Kv channel-interacting protein 2 (KChIP2), or A-type potassium channel modulatory protein 2, or Potassium channel-interacting protein 2, and encoded by the gene Kcnip2/Kchip2, is the regulatory subunit of the Kv4/D Shal-type voltage gated inactivating potassium channel. KCHIP2 modulates the activities of Kv4.2 and Kv4.3 potassium channels. KCHIP2 is localized to the cell membrane but is a peripheral membrane protein. KCHIP2 is expressed in heart, brain and lung. In brain, KCHIP2 is abundantly expressed in striatum, hippocampus, and olfactory bulb, but moderate to low expression is seen in cerebral cortex thalamus and hypothalamus. KCHIP2 has multiple isoforms in the different tissues. Isoform 1 is predominant in cerebral cortex, striatum and hippocampus, and all three isoforms are equally expressed in olfactory bulb, but in heart only isoform 3 predominates.
      References
      Product Information
      FormatPurified
      PresentationPurified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
      Quality LevelMQ100
      Applications
      ApplicationThis Anti-KChIP2 potassium channel subunit Antibody, clone 60/73 is validated for use in western blotting & IHC for the detection of KChIP2 potassium channel subunit.
      Key Applications
      • Western Blotting
      • Immunohistochemistry
      Application NotesImmunohistochemistry Analysis: A 1:50 dilution from a representative lot detected KChIP2 potassium channel subunit in human cerebral cortex tissue.
      Biological Information
      ImmunogenGST-tagged recombinant protein corresponding to rat KChIP2 potassium channel subunit.
      Clone60/73
      ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
      HostMouse
      SpecificityThis antibody does not cross react with rat KChIP1 and KChIP3 (Prof. J. Trimmer, University of California, Davis).
      IsotypeIgG1κ
      Species Reactivity
      • Mouse
      • Rat
      • Human
      Antibody TypeMonoclonal Antibody
      Entrez Gene Number
      Gene Symbol
      • Kcnip2
      • Kchip2
      Purification MethodProtein G Purified
      UniProt Number
      Molecular Weight~ 35 kDa observed. Uncharacterized band(s) may appear in some lysates.
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blotting in mouse brain tissue lysate.

      Western Blotting Analysis: 1.0 µg/mL of this antibody detected KChIP2 potassium channel subunit in 10 µg of mouse brain tissue lysate.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Packaging Information
      Material Size100 µg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalog Number GTIN
      MABN371 04053252943263

      Documentation

      Anti-KChIP2 potassium channel subunit Antibody, clone 60/73 Certificates of Analysis

      TitleLot Number
      Anti-KChIP2 potassium channel -2695329 2695329
      Anti-KChIP2 potassium channel subunit, clone 60/73 - Q2355211 Q2355211
      Anti-KChIP2 potassium channel subunit, clone 60/73 - 3277104 3277104
      Anti-KChIP2 potassium channel subunit, clone 60/73 - 3670715 3670715
      Anti-KChIP2 potassium channel subunit, clone 60/73 -2653163 2653163
      Anti-KChIP2 potassium channel subunit, clone 60/73 Monoclonal Antibody 2970637