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AB10428 Anti-Kallikrein-3 (KLK3) (CT) Antibody

This Anti-Kallikrein-3 (KLK3) (C-term) Antibody is validated for use in WB for the detection of Kallikrein-3 (KLK3) (C-term).

Anti-Kallikrein-3 (KLK3) (CT) Antibody MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Apoptosis & Cancer Research Sub-Category: Apoptosis - Additional Gene Symbol: APS, EC 3.4.21.77, Gamma-seminoprotein , KLK2A1, Kallikrein-3, PSA , Semenogelase, Seminin, hK3 UniProt Number: P07288
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AB10428
400 µl  
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      Key Specifications Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      H, M, RWBRbPurifiedPolyclonal Antibody
      Description
      Catalogue NumberAB10428
      DescriptionAnti-Kallikrein-3 (KLK3) (CT) Antibody
      Alternate Names
      • P-30 antigen
      • Kallikrein-3
      • kallikrein-related peptidase 3
      Background InformationKallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. KLK3 is a protease present in seminal plasma. It is thought to function normally in the liquefaction of seminal coagulum, presumably by hydrolysis of the high molecular mass seminal vesicle protein.
      References
      Product Information
      FormatPurified
      Control
      • Western Blot : Mouse brain lysate.
      PresentationPurified in PBS with 0.09% NaN3.
      Quality LevelMQ100
      Applications
      ApplicationThis Anti-Kallikrein-3 (KLK3) (C-term) Antibody is validated for use in WB for the detection of Kallikrein-3 (KLK3) (C-term).
      Key Applications
      • Western Blotting
      Biological Information
      ImmunogenThis antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human KLK3.
      ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
      HostRabbit
      SpecificityThe antibody reacts with the 29 kDa KLK3 antigen.
      Species Reactivity
      • Human
      • Mouse
      • Rat
      Species Reactivity NoteReacts with human, mouse and rat. Other species have not been tested.
      Antibody TypePolyclonal Antibody
      Entrez Gene Number
      Entrez Gene SummaryKallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its protein product is a protease present in seminal plasma. It is thought to function normally in the liquefaction of seminal coagulum, presumably by hydrolysis of the high molecular mass seminal vesicle protein. [provided by RefSeq]
      Gene Symbol
      • APS
      • EC 3.4.21.77
      • Gamma-seminoprotein
      • KLK2A1
      • Kallikrein-3
      • PSA
      • Semenogelase
      • Seminin
      • hK3
      Purification MethodSaturated Ammonium Sulfate (SAS)
      UniProt Number
      UniProt SummaryFUNCTION: Hydrolyzes semenogelin-1 thus leading to the liquefaction of the seminal coagulum.
      CATALYTIC ACTIVITY: Preferential cleavage: -Tyr-|-Xaa-.
      SUBCELLULAR LOCATION: Secreted.
      SEQUENCE SIMILARITIES: Belongs to the peptidase S1 family. Kallikrein subfamily.
      Contains 1 peptidase S1 domain.
      Molecular Weight~31 kDa observed.
      Band may migrate from the calculated 29 kDa to ~31 kDa on western blot.
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceWestern Blot Analysis: 1:250 dilution of this antibody detected KLK3 on mouse brain lysate.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStore at 2-8°C for 6 months from date of receipt. For long term storage, store at -20°
      Packaging Information
      Material Size400 µl
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalog Number GTIN
      AB10428 04053252286025