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MABC1720

Sigma-Aldrich

Anti-PMEL Antibody, clone HMB-45

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41
Pricing and availability is not currently available.

antibody form

purified antibody

clone

HMB-45
monoclonal

purified by

using protein G

species reactivity

human, mouse, human

concentration

(Please refer to lot specific datasheet.)

technique(s)

immunohistochemistry: suitable

isotype

IgG1κ

UniProt accession no.

P40967

General description

Pigmented melanoma metastases extracted from human lymph nodes.

Specificity

Clone HMB-45 is a mouse monoclonal antibody that detects human Melanocyte protein PMEL.

Application

Immunohistochemistry (Paraffin) Analysis: A 1:250 dilution from a representative lot detected PMEL in human melanoma tissue sections.

Immunohistochemistry (Paraffin) Analysis: A representative lot detected PMEL in Immunohistochemistry applications (Gown, A.M., et. al. (1986). Am J Pathol. 123(2):195-203).

Quality

Evaluated by Immunohistochemistry (Paraffin) in human skin tissue sections.

Immunohistochemistry (Paraffin) Analysis: A 1:250 dilution of this antibody detected PMEL in human skin tissue sections.

Physical properties

70.25 kDa calculated.

Physical form

Purified mouse monoclonal antibody IgG1 in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Storage and Stability

Stable for 1 year at 2-8°C from date of receipt.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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