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ABC1486 Anti-RIPK1 Antibody

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ABC1486
100 μg  
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      Overview

      Replacement Information

      Key Specifications Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      R, MWB, IHCRbAffinity PurifiedPolyclonal Antibody
      Description
      Catalogue NumberABC1486
      DescriptionAnti-RIPK1 Antibody
      Alternate Names
      • Receptor-interacting serine/threonine-protein kinase 1
      • RIPK1
      Background InformationReceptor-interacting serine/threonine-protein kinase 1, also known as Cell death protein RIP or Receptor-interacting protein 1 (RIP-1) or Serine/threonine-protein kinase RIP, and encoded by the gene name RIPK1 or RIP or RIP1, contains 1 death domain and 1 protein kinase domain. RIPK1 is localized to the cytoplasm and plays an important role in a variety of cellular pathways including the NF-κB pathway and programmed necrotic cell death (necroptosis).
      References
      Product Information
      FormatAffinity Purified
      PresentationPurified rabbit polyclonal in buffer containing PBS (pH 7.2) with 0.02% sodium azide.
      Quality LevelMQ100
      Applications
      ApplicationThis Anti-RIPK1 Antibody is validated for use in Western Blotting_x000D_ and Immunohistochemistry for the detection of RIPK1.
      Key Applications
      • Western Blotting
      • Immunohistochemistry
      Application NotesImmunohistochemistry Analysis (IHC): 2.5 μg/mL from a representative lot detected RIPK1 in mouse kidney tissue.

      Biological Information
      ImmunogenRIPK1 antibody was raised against a 15 amino acid synthetic peptide from near the amino terminus of human RIPK1.
      EpitopeNear N-terminus
      ConcentrationPlease refer to lot specific datasheet.
      HostRabbit
      Species Reactivity
      • Rat
      • Mouse
      Antibody TypePolyclonal Antibody
      Gene Symbol
      • RIPK1
      • RIP
      • RIP1
      Purification MethodAntigen Affinity Purified
      UniProt Number
      Molecular Weight~75 kDa observed. Uncharacterized bands may be observed in some lysate(s).
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blotting in rat kidney tissue lysate.

      Western Blotting Analysis (WB): 1 μg/mL of this antibody detected RIPK1 in rat kidney tissue lysate.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Packaging Information
      Material Size100 μg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalog Number GTIN
      ABC1486 04055977174632

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      Catalog Number Description  
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      Categories

      Life Science Research > Antibodies and Assays > Primary Antibodies